Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2188281..2188549 Replicon chromosome
Accession NZ_CP028768
Organism Escherichia coli strain A6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2188409..2188511 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2188281..2188549 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY57_RS10620 2184835..2185497 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY57_RS10625 2185520..2186176 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
AOY57_RS10630 2186278..2186508 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY57_RS10635 2186647..2187021 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AOY57_RS10640 2187025..2187897 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
AOY57_RS10645 2187910..2188251 + 342 WP_000976472.1 YebY family protein -
- 2188281..2188549 - 269 - - Antitoxin
- 2188409..2188511 + 103 - - Toxin
AOY57_RS10650 2188646..2189302 + 657 WP_001357783.1 protein-serine/threonine phosphatase -
AOY57_RS10655 2189303..2189494 - 192 WP_001317886.1 YebW family protein -
AOY57_RS10660 2189599..2189835 - 237 WP_001295499.1 YebV family protein -
AOY57_RS10665 2189953..2191392 - 1440 WP_201478593.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T103990 NZ_CP028768:2188409-2188511 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT103990 NZ_CP028768:c2188549-2188281 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References