Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2176798..2177066 Replicon chromosome
Accession NZ_CP028764
Organism Escherichia coli strain A10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2176925..2177028 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2176798..2177066 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY63_RS10240 2173351..2174013 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY63_RS10245 2174037..2174693 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
AOY63_RS10250 2174795..2175025 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY63_RS10255 2175164..2175538 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AOY63_RS10260 2175542..2176414 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
AOY63_RS10265 2176427..2176768 + 342 WP_000976472.1 YebY family protein -
- 2176798..2177066 - 269 - - Antitoxin
- 2176925..2177028 + 104 - - Toxin
AOY63_RS10270 2177163..2177819 + 657 WP_201477176.1 protein-serine/threonine phosphatase -
AOY63_RS10275 2177820..2178011 - 192 WP_001296140.1 YebW family protein -
AOY63_RS10280 2178116..2178352 - 237 WP_001295499.1 YebV family protein -
AOY63_RS10285 2178470..2179909 - 1440 WP_024174147.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2153005..2192906 39901


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103890 NZ_CP028764:2176925-2177028 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT103890 NZ_CP028764:c2177066-2176798 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References