Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2121151..2121422 Replicon chromosome
Accession NZ_CP028762
Organism Escherichia coli strain A12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2121281..2121384 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2121151..2121422 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY65_RS10200 2117706..2118368 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY65_RS10205 2118392..2119048 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
AOY65_RS10210 2119150..2119380 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY65_RS10215 2119519..2119893 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AOY65_RS10220 2119897..2120769 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AOY65_RS10225 2120782..2121123 + 342 WP_000976492.1 YebY family protein -
- 2121151..2121422 - 272 - - Antitoxin
- 2121281..2121384 + 104 - - Toxin
AOY65_RS10230 2121519..2122175 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AOY65_RS10235 2122176..2122367 - 192 WP_001296140.1 YebW family protein -
AOY65_RS10240 2122472..2122708 - 237 WP_001295499.1 YebV family protein -
AOY65_RS10245 2122826..2124265 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103846 NZ_CP028762:2121281-2121384 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT103846 NZ_CP028762:c2121422-2121151 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References