Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2125128..2125399 Replicon chromosome
Accession NZ_CP028756
Organism Escherichia coli strain A19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2125258..2125361 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2125128..2125399 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY72_RS10245 2121683..2122345 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY72_RS10250 2122369..2123025 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
AOY72_RS10255 2123127..2123357 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY72_RS10260 2123496..2123870 + 375 WP_000204699.1 CopC domain-containing protein YobA -
AOY72_RS10265 2123874..2124746 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AOY72_RS10270 2124759..2125100 + 342 WP_000976492.1 YebY family protein -
- 2125128..2125399 - 272 - - Antitoxin
- 2125258..2125361 + 104 - - Toxin
AOY72_RS10275 2125496..2126152 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AOY72_RS10280 2126153..2126344 - 192 WP_001296140.1 YebW family protein -
AOY72_RS10285 2126449..2126685 - 237 WP_001295499.1 YebV family protein -
AOY72_RS10290 2126803..2128242 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103690 NZ_CP028756:2125258-2125361 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT103690 NZ_CP028756:c2125399-2125128 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References