Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2060515..2060783 Replicon chromosome
Accession NZ_CP028753
Organism Escherichia coli strain A22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2060643..2060745 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2060515..2060783 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY75_RS09690 2057069..2057731 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY75_RS09695 2057754..2058410 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
AOY75_RS09700 2058512..2058742 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY75_RS09705 2058881..2059255 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AOY75_RS09710 2059259..2060131 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
AOY75_RS09715 2060144..2060485 + 342 WP_000976472.1 YebY family protein -
- 2060515..2060783 - 269 - - Antitoxin
- 2060643..2060745 + 103 - - Toxin
AOY75_RS09720 2060880..2061536 + 657 WP_000812742.1 protein-serine/threonine phosphatase -
AOY75_RS09725 2061537..2061728 - 192 WP_001317886.1 YebW family protein -
AOY75_RS09730 2061833..2062069 - 237 WP_001295499.1 YebV family protein -
AOY75_RS09735 2062187..2063626 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T103607 NZ_CP028753:2060643-2060745 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT103607 NZ_CP028753:c2060783-2060515 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References