Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2028536..2028807 Replicon chromosome
Accession NZ_CP028752
Organism Escherichia coli strain A23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2028666..2028769 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2028536..2028807 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY76_RS09750 2025091..2025753 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY76_RS09755 2025777..2026433 - 657 WP_240770928.1 carbon-nitrogen hydrolase family protein YobB -
AOY76_RS09760 2026535..2026765 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY76_RS09765 2026904..2027278 + 375 WP_000255065.1 CopC domain-containing protein YobA -
AOY76_RS09770 2027282..2028154 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
AOY76_RS09775 2028167..2028508 + 342 WP_000976472.1 YebY family protein -
- 2028536..2028807 - 272 - - Antitoxin
- 2028666..2028769 + 104 - - Toxin
AOY76_RS09780 2028904..2029560 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
AOY76_RS09785 2029561..2029752 - 192 WP_001338167.1 YebW family protein -
AOY76_RS09790 2029857..2030093 - 237 WP_240770929.1 DUF1480 family protein -
AOY76_RS09795 2030211..2031650 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103588 NZ_CP028752:2028666-2028769 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT103588 NZ_CP028752:c2028807-2028536 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References