Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2175044..2175315 Replicon chromosome
Accession NZ_CP028747
Organism Escherichia coli strain A28

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2175174..2175277 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2175044..2175315 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY81_RS10640 2171599..2172261 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY81_RS10645 2172285..2172941 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
AOY81_RS10650 2173043..2173273 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY81_RS10655 2173412..2173786 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AOY81_RS10660 2173790..2174662 + 873 WP_000879273.1 copper homeostasis membrane protein CopD -
AOY81_RS10665 2174675..2175016 + 342 WP_000976492.1 YebY family protein -
- 2175044..2175315 - 272 - - Antitoxin
- 2175174..2175277 + 104 - - Toxin
AOY81_RS10670 2175412..2176068 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AOY81_RS10675 2176069..2176260 - 192 WP_001296140.1 YebW family protein -
AOY81_RS10680 2176365..2176601 - 237 WP_001295499.1 YebV family protein -
AOY81_RS10685 2176719..2178158 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103467 NZ_CP028747:2175174-2175277 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT103467 NZ_CP028747:c2175315-2175044 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References