Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2023079..2023350 Replicon chromosome
Accession NZ_CP028737
Organism Escherichia coli strain A39

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2023209..2023312 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2023079..2023350 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY92_RS09820 2019634..2020296 - 663 WP_000944256.1 exodeoxyribonuclease X -
AOY92_RS09825 2020320..2020976 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
AOY92_RS09830 2021078..2021308 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY92_RS09835 2021447..2021821 + 375 WP_240758065.1 CopC domain-containing protein YobA -
AOY92_RS09840 2021825..2022697 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
AOY92_RS09845 2022710..2023051 + 342 WP_000976492.1 YebY family protein -
- 2023079..2023350 - 272 - - Antitoxin
- 2023209..2023312 + 104 - - Toxin
AOY92_RS09850 2023447..2024103 + 657 WP_021565248.1 protein-serine/threonine phosphatase -
AOY92_RS09855 2024104..2024295 - 192 WP_000457842.1 YebW family protein -
AOY92_RS09860 2024400..2024636 - 237 WP_001295499.1 YebV family protein -
AOY92_RS09865 2024754..2026193 - 1440 WP_024235159.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T103211 NZ_CP028737:2023209-2023312 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT103211 NZ_CP028737:c2023350-2023079 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References