Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2160060..2160328 Replicon chromosome
Accession NZ_CP028734
Organism Escherichia coli strain A42

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2160188..2160290 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2160060..2160328 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY95_RS10360 2156614..2157276 - 663 WP_000944249.1 exodeoxyribonuclease X -
AOY95_RS10365 2157300..2157956 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
AOY95_RS10370 2158058..2158288 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AOY95_RS10375 2158427..2158801 + 375 WP_000255065.1 CopC domain-containing protein YobA -
AOY95_RS10380 2158805..2159677 + 873 WP_001607483.1 copper homeostasis membrane protein CopD -
AOY95_RS10385 2159689..2160030 + 342 WP_000976472.1 YebY family protein -
- 2160060..2160328 - 269 - - Antitoxin
- 2160188..2160290 + 103 - - Toxin
AOY95_RS10390 2160425..2161081 + 657 WP_001607480.1 protein-serine/threonine phosphatase -
AOY95_RS10395 2161082..2161273 - 192 WP_218068858.1 YebW family protein -
AOY95_RS10400 2161378..2161614 - 237 WP_001295499.1 YebV family protein -
AOY95_RS10405 2161731..2163170 - 1440 WP_024186908.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T103157 NZ_CP028734:2160188-2160290 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT103157 NZ_CP028734:c2160328-2160060 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References