Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 2232344..2234060 Replicon chromosome
Accession NZ_CP028730
Organism Shewanella baltica strain 128

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag C7T95_RS09665 Protein ID WP_107947368.1
Coordinates 2233125..2234060 (+) Length 312 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag C7T95_RS09660 Protein ID WP_107947366.1
Coordinates 2232344..2233132 (+) Length 263 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7T95_RS09630 2227349..2227684 + 336 WP_107947355.1 helix-turn-helix domain-containing protein -
C7T95_RS09635 2227671..2228912 + 1242 WP_107947358.1 HipA domain-containing protein -
C7T95_RS09640 2228913..2229344 + 432 WP_107947360.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
C7T95_RS09645 2229688..2230509 + 822 WP_107946805.1 GNAT family N-acetyltransferase -
C7T95_RS09650 2230602..2231453 + 852 WP_107947362.1 AraC family transcriptional regulator -
C7T95_RS09655 2231691..2232089 - 399 WP_107947364.1 hypothetical protein -
C7T95_RS09660 2232344..2233132 + 789 WP_107947366.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
C7T95_RS09665 2233125..2234060 + 936 WP_107947368.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
C7T95_RS09670 2234177..2234587 - 411 WP_107947370.1 hypothetical protein -
C7T95_RS09675 2234624..2234884 - 261 WP_107947372.1 hypothetical protein -
C7T95_RS21430 2235248..2235625 + 378 WP_199908829.1 hypothetical protein -
C7T95_RS09680 2235576..2236244 + 669 Protein_1846 IS3 family transposase -
C7T95_RS09685 2236252..2236896 + 645 Protein_1847 peptidase S51 -
C7T95_RS09690 2237246..2237746 - 501 WP_006081478.1 peptidyl-prolyl cis-trans isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2208714..2235163 26449
- flank IS/Tn - - 2235582..2236154 572


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-266)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(100-250)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 35330.17 Da        Isoelectric Point: 7.4700

>T103093 WP_107947368.1 NZ_CP028730:2233125-2234060 [Shewanella baltica]
MNKSSIYYQQVTLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAKINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGISREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLDELILTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSVAALPAVRWKLLNIQNLAKNKSKHQEQLIKLANVLDTWVAGRIL

Download         Length: 936 bp

>T103093 NZ_CP028730:2233125-2234060 [Shewanella baltica]
ATGAATAAGTCATCGATATACTACCAGCAAGTGACCTTGCTTATTCGGATGCTGCCGCTCGTCGCCCAAGAGAAGGTATT
TGCCCTAAAGGGCGGTACGGCTATCAACCTATTTGTACGCAACTTCCCACGCTTATCGGTTGATATCGATTTGGCTTATC
TTCCTTTGGAGCCAAGGGAACAAGCGCTACAAAGTGTGAAGGAAGCGCTTGGTCGTTTGACTGCGAAGATCAATCTACAA
CCGAACCTTAGTGCAGTATTTCAAGACAATAAATATGATGAGCTCAGGGTTGTCGTGACAAGTGATAGGGTGACAATAAA
AATTGAAGTCTCTCCTGTTGCGAGAGGTACGCTACACAAAGCGGTATTAATGCCAGTCGTTGAGTTAGTTGAAGAAGAAT
TTGGGTATGCAGAGATACCGGTTGTAAGCCTGCCTGATCTATACGGTGGTAAGTTATGTGCAGCGATGGATAGGCAGCAC
CCAAGGGATCTTTTCGATGTGAAAATGCTGCTGGCGGAAGAGGGGATCAGTCGAGAGATTTTAGTCGGCTTTCTCACTTA
TACACTTAGCCATCCAAGACCCATTAATGAAGTGATGTCTCCACGTTGGAAACCGCTTGATGAAAGCTTTCAAACTGAAT
TCAATGGAATGACGACAAAGCCGATTAAACTCGATGAGCTGATTTTAACTCGCTCAGAAATGCTAACAGCGTTGCAGCAT
CACTTTACTGCAAAAGATAGAGACTTTTTATTATCCTTTAAACAGGGTCAGCCTGATTGGTCATTGTTTGATGAACCGAG
CGTTGCGGCACTACCTGCGGTGAGATGGAAGCTATTGAATATCCAAAATCTAGCGAAAAACAAATCCAAGCATCAAGAAC
AACTCATTAAACTGGCTAATGTATTGGATACGTGGGTTGCCGGTCGGATACTCTAA

Antitoxin


Download         Length: 263 a.a.        Molecular weight: 29882.98 Da        Isoelectric Point: 9.3615

>AT103093 WP_107947366.1 NZ_CP028730:2232344-2233132 [Shewanella baltica]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPESTGKLQPHWVEALKALNEQLKLPVHL
AGVSSLTHQGLSHYLQLSSEQVWVGCQSKQALPKWFRELEEQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRKIQSILNRSEAVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDGRYQITVPASFIKTEENQYE

Download         Length: 789 bp

>AT103093 NZ_CP028730:2232344-2233132 [Shewanella baltica]
ATGTCGTCAAAAATAAACTGGCTGATTAATCATACGAGTCCTGGTGCGGTAGTGCTTCAGTCGTGGTTGACACAAAATGA
GATCAGCTCATCTTTGGTGAGAAAATATGTGCAGAGTGGTTGGTTGTACAAGATAAGTGCGGGGGTTTACGTTCGTCCTG
AGTCAACAGGTAAGTTACAGCCTCATTGGGTTGAAGCGCTCAAGGCTTTGAATGAGCAGCTAAAGCTTCCTGTTCACCTT
GCGGGAGTCAGTAGCCTAACGCATCAAGGGCTTAGTCATTATCTTCAACTAAGCAGCGAGCAAGTTTGGGTTGGCTGTCA
AAGTAAGCAGGCGTTGCCAAAGTGGTTCCGCGAATTGGAGGAGCAAAATTGGCTTTTCTATACCAGTAGCAAGCTGACCC
AAACGTTAGAAAAAGACTTTATTACTATAGGGGTGAACAATAGGGAAGTTAAGGCAAGTTGTGCGGAGCTTGCAGCCTAT
GAGGTCGTCAATGCCATTGGCAAACATATCAGTTTTGAGCATGCCGCGGAGCTGTTTCAAGGGTTAGTGAATCTCAGCCC
ACGTAAAATACAGTCAATACTGAATCGAAGTGAAGCCGTACAAGCTAATCGCGTATTTCTCTTTTTAGGCCACTACTATC
AACACCAGTGGAGCAAAAGGCTAGATGAGCAGCAAATCACGCTAGGCGCGGGAAAGCGTCAGGTGGTGGCTCATGGCCGT
TACGATGGGCGGTATCAAATAACAGTGCCTGCATCGTTTATTAAGACAGAAGAAAATCAATATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References