Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 1322040..1323756 Replicon chromosome
Accession NZ_CP028730
Organism Shewanella baltica strain 128

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag C7T95_RS05545 Protein ID WP_107404662.1
Coordinates 1322821..1323756 (+) Length 312 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag C7T95_RS05540 Protein ID WP_106649805.1
Coordinates 1322040..1322828 (+) Length 263 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7T95_RS05510 1317046..1317381 + 336 WP_107946803.1 helix-turn-helix domain-containing protein -
C7T95_RS05515 1317368..1318609 + 1242 WP_107946804.1 HipA domain-containing protein -
C7T95_RS05520 1318610..1319041 + 432 WP_107404666.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
C7T95_RS05525 1319385..1320206 + 822 WP_107946805.1 GNAT family N-acetyltransferase -
C7T95_RS05530 1320299..1321150 + 852 WP_107946806.1 AraC family transcriptional regulator -
C7T95_RS05535 1321388..1321785 - 398 Protein_1056 hypothetical protein -
C7T95_RS05540 1322040..1322828 + 789 WP_106649805.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
C7T95_RS05545 1322821..1323756 + 936 WP_107404662.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
C7T95_RS05550 1323875..1324285 - 411 WP_107404661.1 hypothetical protein -
C7T95_RS05555 1324322..1324579 - 258 WP_107946807.1 hypothetical protein -
C7T95_RS05560 1324697..1326157 - 1461 WP_107946808.1 site-specific integrase -
C7T95_RS05565 1326346..1326732 + 387 WP_107404063.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1301982..1327262 25280


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 312 a.a.        Molecular weight: 35345.19 Da        Isoelectric Point: 7.0666

>T103091 WP_107404662.1 NZ_CP028730:1322821-1323756 [Shewanella baltica]
MNKSSIYYQQVTLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAKINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGISREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLDELILTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSVAALPAVRWKLLNIQNLAKNKSKHQEQLIKLADVLETWVAGRIL

Download         Length: 936 bp

>T103091 NZ_CP028730:1322821-1323756 [Shewanella baltica]
ATGAATAAGTCATCGATATACTACCAGCAAGTGACCTTGCTTATTCGGATGCTGCCGCTCGTCGCCCAAGAGAAGGTATT
TGCCCTAAAGGGCGGTACGGCTATCAACCTATTTGTACGCAACTTCCCACGCTTATCGGTTGATATCGATTTGGCTTATC
TTCCTTTGGAGCCAAGGGAACAAGCGCTACAAAGTGTGAAGGAAGCGCTTGGTCGTTTGACTGCGAAGATCAATCTACAA
CCGAACCTTAGTGCAGTATTTCAAGACAATAAATATGATGAGCTCAGGGTTGTCGTGACAAGTGATAGGGTGACAATAAA
AATTGAAGTCTCTCCTGTTGCGAGAGGTACGCTACACAAAGCGGTATTAATGCCAGTCGTTGAGTTAGTTGAAGAAGAAT
TTGGGTATGCAGAGATACCGGTTGTAAGCCTGCCTGATCTATACGGTGGTAAGTTATGTGCAGCGATGGATAGGCAGCAC
CCAAGGGATCTTTTCGATGTGAAAATGCTGCTGGCGGAAGAGGGGATCAGTCGAGAGATTTTAGTCGGCTTTCTCACTTA
TACACTTAGCCATCCAAGACCCATTAATGAAGTGATGTCTCCACGTTGGAAACCGCTTGATGAAAGCTTTCAAACTGAAT
TCAATGGAATGACGACAAAGCCGATTAAACTCGATGAGCTGATTTTAACTCGCTCAGAAATGCTCACAGCGTTGCAGCAT
CACTTTACTGCAAAAGATAGAGACTTTTTATTATCCTTTAAACAGGGTCAGCCTGATTGGTCATTGTTTGATGAACCGAG
CGTTGCGGCACTACCTGCGGTGAGATGGAAGCTATTGAATATCCAAAACCTAGCGAAAAATAAATCCAAGCATCAAGAAC
AACTGATTAAACTGGCTGATGTATTGGAGACGTGGGTTGCAGGTCGGATATTGTAA

Antitoxin


Download         Length: 263 a.a.        Molecular weight: 29868.96 Da        Isoelectric Point: 9.3615

>AT103091 WP_106649805.1 NZ_CP028730:1322040-1322828 [Shewanella baltica]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPESTGKLQPHWVEALKAVNEQLKLPVHL
AGVSSLTHQGLSHYLQLSSEQVWVGCQSKQALPKWFRELEEQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRKIQSILNRSEAVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDGRYQITVPASFIKTEENQYE

Download         Length: 789 bp

>AT103091 NZ_CP028730:1322040-1322828 [Shewanella baltica]
ATGTCATCAAAAATAAACTGGCTGATTAATCATACGAGTCCTGGTGCGGTAGTGCTTCAGTCGTGGTTAACACAAAATGA
GATCAGCTCATCTTTGGTGAGAAAATATGTGCAGAGTGGTTGGTTGTACAAGATAAGTGCGGGGGTTTACGTTCGTCCTG
AGTCAACAGGTAAGTTACAGCCTCATTGGGTTGAAGCGCTCAAGGCTGTGAATGAGCAGCTAAAGCTTCCTGTTCACCTT
GCGGGAGTCAGTAGCCTAACGCATCAAGGGCTTAGTCATTATCTTCAACTAAGCAGCGAGCAAGTTTGGGTTGGCTGTCA
AAGTAAGCAGGCGTTGCCAAAGTGGTTCCGCGAATTGGAGGAGCAAAATTGGCTTTTCTATACCAGTAGCAAGCTGACCC
AAACGTTAGAAAAAGACTTTATTACTATAGGGGTGAACAATAGGGAAGTTAAGGCAAGTTGTGCGGAGCTTGCAGCCTAT
GAGGTCGTCAATGCCATTGGCAAACATATCAGTTTTGAGCATGCCGCGGAGCTGTTTCAAGGGTTAGTGAATCTCAGCCC
ACGTAAAATACAGTCAATACTGAATCGAAGTGAAGCCGTACAAGCTAATCGCGTATTTCTCTTTTTAGGCCACTACTATC
AACACCAGTGGAGCAAAAGGCTAGATGAGCAGCAAATCACGCTAGGCGCGGGAAAGCGTCAGGTGGTGGCTCATGGCCGT
TACGATGGACGGTATCAAATAACAGTGCCTGCATCGTTTATTAAGACAGAAGAAAATCAATATGAATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References