Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4004334..4004479 Replicon chromosome
Accession NZ_CP028716
Organism Klebsiella pneumoniae strain SCM96

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4004341..4004443 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4004334..4004479 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA106_RS20070 3999865..4001298 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DA106_RS20075 4001414..4001653 + 240 WP_002911393.1 YebV family protein -
DA106_RS20080 4001751..4001942 + 192 WP_002911395.1 YebW family protein -
DA106_RS20085 4001939..4002592 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
DA106_RS20090 4002749..4003717 + 969 WP_004151446.1 VirK/YbjX family protein -
DA106_RS28295 4003822..4003965 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4004334..4004479 + 146 - - Antitoxin
- 4004341..4004443 - 103 - - Toxin
DA106_RS20100 4004602..4004940 - 339 WP_002911404.1 YebY family protein -
DA106_RS20105 4004957..4005826 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
DA106_RS20110 4005830..4006204 - 375 WP_004151448.1 CopC domain-containing protein YobA -
DA106_RS20115 4006317..4006547 + 231 WP_002911406.1 DNA polymerase III subunit theta -
DA106_RS20120 4006626..4007285 + 660 WP_020324964.1 exodeoxyribonuclease X -
DA106_RS20125 4007289..4009349 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T103029 NZ_CP028716:c4004443-4004341 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT103029 NZ_CP028716:4004334-4004479 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References