Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2356394..2356665 Replicon chromosome
Accession NZ_CP028702
Organism Escherichia coli strain J53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2356432..2356535 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2356394..2356665 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBB46_RS12405 2353551..2354990 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
DBB46_RS12410 2355108..2355344 + 237 WP_001295499.1 DUF1480 family protein -
DBB46_RS12415 2355449..2355640 + 192 WP_000457842.1 YebW family protein -
DBB46_RS12420 2355641..2356297 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2356394..2356665 + 272 - - Antitoxin
- 2356432..2356535 - 104 - - Toxin
DBB46_RS12425 2356693..2357034 - 342 WP_000976476.1 YebY family protein -
DBB46_RS12430 2357047..2357919 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
DBB46_RS12435 2357923..2358297 - 375 WP_000168747.1 CopC domain-containing protein YobA -
DBB46_RS12440 2358436..2358666 + 231 WP_000916763.1 DNA polymerase III subunit theta -
DBB46_RS12445 2358768..2359424 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DBB46_RS12450 2359448..2360110 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102959 NZ_CP028702:c2356535-2356432 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102959 NZ_CP028702:2356394-2356665 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References