Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2174475..2174746 Replicon chromosome
Accession NZ_CP028698
Organism Escherichia coli strain 106

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2174605..2174708 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2174475..2174746 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E35_RS10945 2171030..2171692 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E35_RS10950 2171716..2172372 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E35_RS10955 2172474..2172704 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E35_RS10960 2172843..2173217 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E35_RS10965 2173221..2174093 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E35_RS10970 2174106..2174447 + 342 WP_000976483.1 YebY family protein -
- 2174475..2174746 - 272 - - Antitoxin
- 2174605..2174708 + 104 - - Toxin
C9E35_RS10975 2174843..2175499 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E35_RS10980 2175500..2175691 - 192 WP_001296140.1 YebW family protein -
C9E35_RS10985 2175796..2176032 - 237 WP_001295499.1 DUF1480 family protein -
C9E35_RS10990 2176150..2177589 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102882 NZ_CP028698:2174605-2174708 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102882 NZ_CP028698:c2174746-2174475 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References