Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2192994..2193265 Replicon chromosome
Accession NZ_CP028687
Organism Escherichia coli strain 110

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2193124..2193227 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2192994..2193265 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E39_RS11090 2189549..2190211 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E39_RS11095 2190235..2190891 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E39_RS11100 2190993..2191223 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E39_RS11105 2191362..2191736 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E39_RS11110 2191740..2192612 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E39_RS11115 2192625..2192966 + 342 WP_000976483.1 YebY family protein -
- 2192994..2193265 - 272 - - Antitoxin
- 2193124..2193227 + 104 - - Toxin
C9E39_RS11120 2193362..2194018 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E39_RS11125 2194019..2194210 - 192 WP_001296140.1 YebW family protein -
C9E39_RS11130 2194315..2194551 - 237 WP_001295499.1 DUF1480 family protein -
C9E39_RS11135 2194669..2196108 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102746 NZ_CP028687:2193124-2193227 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102746 NZ_CP028687:c2193265-2192994 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References