Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2188705..2188976 Replicon chromosome
Accession NZ_CP028674
Organism Escherichia coli strain 115

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2188835..2188938 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2188705..2188976 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E44_RS11030 2185260..2185922 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E44_RS11035 2185946..2186602 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E44_RS11040 2186704..2186934 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E44_RS11045 2187073..2187447 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E44_RS11050 2187451..2188323 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E44_RS11055 2188336..2188677 + 342 WP_000976483.1 YebY family protein -
- 2188705..2188976 - 272 - - Antitoxin
- 2188835..2188938 + 104 - - Toxin
C9E44_RS11060 2189073..2189729 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E44_RS11065 2189730..2189921 - 192 WP_001296140.1 YebW family protein -
C9E44_RS11070 2190026..2190262 - 237 WP_001295499.1 DUF1480 family protein -
C9E44_RS11075 2190380..2191819 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102577 NZ_CP028674:2188835-2188938 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102577 NZ_CP028674:c2188976-2188705 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References