Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246250..2246521 Replicon chromosome
Accession NZ_CP028668
Organism Escherichia coli strain 117

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246380..2246483 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246250..2246521 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E46_RS11490 2242805..2243467 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E46_RS11495 2243491..2244147 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E46_RS11500 2244249..2244479 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E46_RS11505 2244618..2244992 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E46_RS11510 2244996..2245868 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E46_RS11515 2245881..2246222 + 342 WP_000976483.1 YebY family protein -
- 2246250..2246521 - 272 - - Antitoxin
- 2246380..2246483 + 104 - - Toxin
C9E46_RS11520 2246618..2247274 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E46_RS11525 2247275..2247466 - 192 WP_001296140.1 YebW family protein -
C9E46_RS11530 2247571..2247807 - 237 WP_001295499.1 DUF1480 family protein -
C9E46_RS11535 2247925..2249364 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102505 NZ_CP028668:2246380-2246483 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102505 NZ_CP028668:c2246521-2246250 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References