Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246219..2246490 Replicon chromosome
Accession NZ_CP028647
Organism Escherichia coli strain 130

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246349..2246452 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246219..2246490 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E54_RS11485 2242774..2243436 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E54_RS11490 2243460..2244116 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E54_RS11495 2244218..2244448 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E54_RS11500 2244587..2244961 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E54_RS11505 2244965..2245837 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E54_RS11510 2245850..2246191 + 342 WP_000976483.1 YebY family protein -
- 2246219..2246490 - 272 - - Antitoxin
- 2246349..2246452 + 104 - - Toxin
C9E54_RS11515 2246587..2247243 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E54_RS11520 2247244..2247435 - 192 WP_001296140.1 YebW family protein -
C9E54_RS11525 2247540..2247776 - 237 WP_001295499.1 DUF1480 family protein -
C9E54_RS11530 2247894..2249333 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T102228 NZ_CP028647:2246349-2246452 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT102228 NZ_CP028647:c2246490-2246219 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References