Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | creTA/- |
| Location | 2730357..2730639 | Replicon | chromosome |
| Accession | NZ_CP028561 | ||
| Organism | Acinetobacter sp. WCHA45 | ||
Toxin (RNA)
| Gene name | creT | ||
| Locus tag | - | ||
| Coordinates | 2730357..2730400 (-) |
Antitoxin (RNA)
| Gene name | creA | ||
| Locus tag | - | ||
| Coordinates | 2730592..2730639 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CDG55_RS14480 (CDG55_14470) | 2726160..2726774 | - | 615 | WP_087536696.1 | type I-F CRISPR-associated endoribonuclease Cas6/Csy4 | - |
| CDG55_RS14485 (CDG55_14475) | 2726774..2727814 | - | 1041 | WP_087536695.1 | type I-F CRISPR-associated protein Csy3 | - |
| CDG55_RS14490 (CDG55_14480) | 2727817..2728923 | - | 1107 | WP_087536694.1 | type I-F CRISPR-associated protein Csy2 | - |
| CDG55_RS14495 (CDG55_14485) | 2728923..2730257 | - | 1335 | WP_087536693.1 | type I-F CRISPR-associated protein Csy1 | - |
| - | 2730357..2730400 | - | 44 | - | - | Toxin |
| - | 2730592..2730639 | + | 48 | - | - | Antitoxin |
| CDG55_RS14500 (CDG55_14490) | 2730664..2734149 | - | 3486 | WP_087536692.1 | type I-F CRISPR-associated helicase Cas3 | - |
| CDG55_RS14505 (CDG55_14495) | 2734146..2735114 | - | 969 | WP_087536691.1 | type I-F CRISPR-associated endonuclease Cas1f | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
References
(1) Rui Wang et al. (2023) Associate toxin-antitoxin with CRISPR-Cas to kill multidrug-resistant pathogens. Nature Communications 14(1):2078. [PubMed:37045931]