Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2245884..2246155 Replicon chromosome
Accession NZ_CP028614
Organism Escherichia coli strain 141

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246014..2246117 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2245884..2246155 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E65_RS11485 2242439..2243101 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E65_RS11490 2243125..2243781 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E65_RS11495 2243883..2244113 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E65_RS11500 2244252..2244626 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E65_RS11505 2244630..2245502 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E65_RS11510 2245515..2245856 + 342 WP_000976483.1 YebY family protein -
- 2245884..2246155 - 272 - - Antitoxin
- 2246014..2246117 + 104 - - Toxin
C9E65_RS11515 2246252..2246908 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E65_RS11520 2246909..2247100 - 192 WP_001296140.1 YebW family protein -
C9E65_RS11525 2247205..2247441 - 237 WP_001295499.1 DUF1480 family protein -
C9E65_RS11530 2247559..2248998 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T101833 NZ_CP028614:2246014-2246117 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT101833 NZ_CP028614:c2246155-2245884 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References