Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2244320..2244591 Replicon chromosome
Accession NZ_CP028607
Organism Escherichia coli strain 143

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2244450..2244553 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2244320..2244591 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E67_RS11460 2240875..2241537 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E67_RS11465 2241561..2242217 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E67_RS11470 2242319..2242549 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E67_RS11475 2242688..2243062 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E67_RS11480 2243066..2243938 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E67_RS11485 2243951..2244292 + 342 WP_000976483.1 YebY family protein -
- 2244320..2244591 - 272 - - Antitoxin
- 2244450..2244553 + 104 - - Toxin
C9E67_RS11490 2244688..2245344 + 657 Protein_2198 protein-serine/threonine phosphatase -
C9E67_RS11495 2245345..2245536 - 192 WP_001296140.1 YebW family protein -
C9E67_RS11500 2245641..2245877 - 237 WP_001295499.1 DUF1480 family protein -
C9E67_RS11505 2245995..2247434 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T101765 NZ_CP028607:2244450-2244553 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT101765 NZ_CP028607:c2244591-2244320 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References