Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2291902..2292173 Replicon chromosome
Accession NZ_CP028603
Organism Escherichia coli strain 144

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2292032..2292135 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2291902..2292173 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E68_RS11750 2288457..2289119 - 663 WP_000944243.1 exodeoxyribonuclease X -
C9E68_RS11755 2289143..2289799 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E68_RS11760 2289901..2290131 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E68_RS11765 2290270..2290644 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E68_RS11770 2290648..2291520 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E68_RS11775 2291533..2291874 + 342 WP_000976483.1 YebY family protein -
- 2291902..2292173 - 272 - - Antitoxin
- 2292032..2292135 + 104 - - Toxin
C9E68_RS11780 2292270..2292926 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E68_RS11785 2292927..2293118 - 192 WP_001296140.1 YebW family protein -
C9E68_RS11790 2293223..2293459 - 237 WP_001295499.1 DUF1480 family protein -
C9E68_RS11795 2293577..2295016 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2284561..2308014 23453


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T101727 NZ_CP028603:2292032-2292135 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT101727 NZ_CP028603:c2292173-2291902 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References