Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2284223..2284494 Replicon chromosome
Accession NZ_CP028598
Organism Escherichia coli strain 148

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2284353..2284456 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2284223..2284494 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9E70_RS11725 2280778..2281440 - 663 WP_000944244.1 exodeoxyribonuclease X -
C9E70_RS11730 2281464..2282120 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
C9E70_RS11735 2282222..2282452 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C9E70_RS11740 2282591..2282965 + 375 WP_000168751.1 CopC domain-containing protein YobA -
C9E70_RS11745 2282969..2283841 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
C9E70_RS11750 2283854..2284195 + 342 WP_000976483.1 YebY family protein -
- 2284223..2284494 - 272 - - Antitoxin
- 2284353..2284456 + 104 - - Toxin
C9E70_RS11755 2284591..2285247 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
C9E70_RS11760 2285248..2285439 - 192 WP_001296140.1 YebW family protein -
C9E70_RS11765 2285544..2285780 - 237 WP_001295499.1 DUF1480 family protein -
C9E70_RS11770 2285898..2287337 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T101656 NZ_CP028598:2284353-2284456 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT101656 NZ_CP028598:c2284494-2284223 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References