Detailed information of TA system TA010165

Experimentally validated

Overview

TA module

• Type: VIII
• Classification (family/domain): SdsR-RyeA/-
• Location: 1923066..1923337
• Replicon: chromosome
• Accession: NC_000913
• Organism: Escherichia coli str. K-12 substr. MG1655

Toxin (RNA)

Gene name	SdsR
Locus tag	-
Coordinates	1923104..1923207 (-)

Antitoxin (RNA)

Gene name	RyeA
Locus tag	-
Coordinates	1923066..1923337 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Sequences

Toxin

Nucleotide

• Length: 104 bp

>T10165 NC_000913:c1923207-1923104 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 272 bp

>AT10165 NC_000913:1923066-1923337 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Antitoxin

References

(1) Jee Soo Choi et al. (2018) The small RNA, SdsR, acts as a novel type of toxin in Escherichia coli. RNA Biology 15(10):1319-1335. [PubMed:30293519]


 experimental literature