Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2041385..2041530 Replicon chromosome
Accession NZ_CP028583
Organism Klebsiella pneumoniae strain WCHKP36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2041421..2041523 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2041385..2041530 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEA75_RS11730 2036515..2038575 + 2061 WP_004151449.1 oligopeptidase B -
CEA75_RS11735 2038579..2039238 - 660 WP_002911407.1 exodeoxyribonuclease X -
CEA75_RS11740 2039317..2039547 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CEA75_RS11745 2039660..2040034 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CEA75_RS11750 2040038..2040907 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CEA75_RS11755 2040921..2041262 + 342 WP_015874944.1 YebY family protein -
- 2041385..2041530 - 146 - - Antitoxin
- 2041421..2041523 + 103 - - Toxin
CEA75_RS11760 2041565..2041756 - 192 WP_004175432.1 hypothetical protein -
CEA75_RS11765 2042146..2043036 - 891 WP_085353163.1 VirK/YbjX family protein -
CEA75_RS11770 2043271..2043924 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CEA75_RS11775 2043921..2044112 - 192 WP_002911395.1 YebW family protein -
CEA75_RS11780 2044210..2044449 - 240 WP_002911393.1 YebV family protein -
CEA75_RS11785 2044565..2045998 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T101510 NZ_CP028583:2041421-2041523 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT101510 NZ_CP028583:c2041530-2041385 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References