Detailed information of TA system TA101466

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 216518..217159
• Replicon: chromosome
• Accession: NZ_CP028574
• Organism: Acinetobacter pittii strain WCHAP005046

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: DBQ26_RS02335
• Protein ID: WP_017481666.1
• Coordinates: 216770..217159 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: F0KQ03
• Locus tag: DBQ26_RS02330
• Protein ID: WP_014207740.1
• Coordinates: 216518..216763 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DBQ26_RS02310	212019..213026	+	1008	WP_002116730.1	DNA-directed RNA polymerase subunit alpha	-
DBQ26_RS02315	213045..213422	+	378	WP_002049717.1	50S ribosomal protein L17	-
DBQ26_RS02320	213604..215094	+	1491	WP_002116796.1	NAD(P)/FAD-dependent oxidoreductase	-
DBQ26_RS02325	215145..216317	-	1173	WP_017481668.1	acyl-CoA dehydrogenase family protein	-
DBQ26_RS02330	216518..216763	+	246	WP_014207740.1	succinate dehydrogenase assembly factor 2	Antitoxin
DBQ26_RS02335	216770..217159	+	390	WP_017481666.1	hypothetical protein	Toxin
DBQ26_RS02340	217930..219018	+	1089	WP_005067288.1	hypothetical protein	-
DBQ26_RS02345	219102..219677	+	576	WP_005067290.1	rhombosortase	-
DBQ26_RS02350	219857..222052	+	2196	WP_005067292.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15553.65 Da
• Isoelectric Point: 8.7390

>T101466 WP_017481666.1 NZ_CP028574:216770-217159 [Acinetobacter pittii]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRAEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVFEKIY

Nucleotide

• Length: 390 bp

>T101466 NZ_CP028574:216770-217159 [Acinetobacter pittii]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGTGTCTCGGTAATATTTCAGCTTTTTGTTGGTTTGGGTTTAGC
AATTTTGCTTTATCAGTTATTAACGCCGATATGGTGGCTATGTGCTGTCATTCTTCTATTTATTGGTTTTATTTTCTTTT
TAAAGCAAGCACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTTCTCGAAAAAAGAAATT
TACCGCGCGGAAATTACTAAAATAATTGATTATCAGTTATTTGTAGTTATTTATCTTGAAGAAACTCCTACGAACATAGC
TATTGTTTGGTTCGATCAGCTTCCTATTCAGCAGTGGAAAAGATTAAAAGTCTTTGAAAAGATCTATTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9833.26 Da
• Isoelectric Point: 4.7037

>AT101466 WP_014207740.1 NZ_CP028574:216518-216763 [Acinetobacter pittii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLKQYVH
G

Nucleotide

• Length: 246 bp

>AT101466 NZ_CP028574:216518-216763 [Acinetobacter pittii]
ATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTTTGACCCGTATGT
AAAAAATTATTATTTAAAAGCTGATCCGGCTGAAAAAGCATTATTTGCAGAGTTGGTTGATCAAGAAGATCCAGATTTAT
TAGATTGGTTCATGGAAGTTTCTGAACCTCCACGTACTGAGTTACGTGAATTTATTTATAAACTAAAACAGTATGTGCAT
GGCTAA

Structures

Antitoxin

• AlphaFold DB: F0KQ03