Detailed information of TA system TA101463

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 151205..151773
• Replicon: plasmid pMCR5_045096
• Accession: NZ_CP028567
• Organism: Aeromonas hydrophila subsp. hydrophila strain WCHAH045096

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: C1A23_RS01300
• Protein ID: WP_101617266.1
• Coordinates: 151480..151773 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C1A23_RS01295
• Protein ID: WP_101617265.1
• Coordinates: 151205..151492 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1A23_RS01285	146312..148909	+	2598	WP_101617259.1	AAA family ATPase	-
C1A23_RS01290	149617..150375	+	759	WP_101617261.1	hypothetical protein	-
C1A23_RS25380	150657..151181	-	525	WP_160839560.1	hypothetical protein	-
C1A23_RS01295	151205..151492	+	288	WP_101617265.1	CopG family ribbon-helix-helix protein	Antitoxin
C1A23_RS01300	151480..151773	+	294	WP_101617266.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C1A23_RS01305	151909..153135	-	1227	WP_021141234.1	transposase	-
C1A23_RS01310	153193..153597	+	405	WP_010674034.1	IS200/IS605-like element ISAs26 family transposase	-
C1A23_RS01315	153656..154192	+	537	WP_107979027.1	sel1 repeat family protein	-
C1A23_RS01320	155195..156064	-	870	WP_148248203.1	replication protein RepA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..241090	241090

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (91-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-86)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 12579.08 Da
• Isoelectric Point: 12.7867

>T101463 WP_101617266.1 NZ_CP028567:151480-151773 [Aeromonas hydrophila subsp. hydrophila]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 294 bp

>T101463 NZ_CP028567:151480-151773 [Aeromonas hydrophila subsp. hydrophila]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 12322.73 Da
• Isoelectric Point: 12.7777

>AT101463 WP_101617265.1 NZ_CP028567:151205-151492 [Aeromonas hydrophila subsp. hydrophila]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKK

Nucleotide

• Length: 288 bp

>AT101463 NZ_CP028567:151205-151492 [Aeromonas hydrophila subsp. hydrophila]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA