Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1122322..1124042 Replicon chromosome
Accession NZ_CP028561
Organism Acinetobacter sp. WCHA45

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag CDG55_RS06745 Protein ID WP_087537449.1
Coordinates 1122322..1122981 (+) Length 220 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag CDG55_RS06750 Protein ID WP_087537450.1
Coordinates 1122978..1124042 (+) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG55_RS06705 (CDG55_06705) 1117397..1118152 - 756 WP_087537443.1 hypothetical protein -
CDG55_RS06710 (CDG55_06710) 1118209..1118676 - 468 WP_087537444.1 hypothetical protein -
CDG55_RS06715 (CDG55_06715) 1118679..1119068 - 390 WP_087537445.1 hypothetical protein -
CDG55_RS06720 (CDG55_06720) 1119186..1119398 - 213 WP_087537446.1 hypothetical protein -
CDG55_RS06725 (CDG55_06725) 1119633..1120136 - 504 WP_087537447.1 hypothetical protein -
CDG55_RS06730 (CDG55_06730) 1120166..1120390 - 225 WP_087537448.1 hypothetical protein -
CDG55_RS06735 (CDG55_06735) 1120526..1120783 - 258 WP_087537452.1 hypothetical protein -
CDG55_RS15385 1121543..1122187 + 645 WP_213066148.1 hypothetical protein -
CDG55_RS06745 (CDG55_06745) 1122322..1122981 + 660 WP_087537449.1 DUF4433 domain-containing protein Toxin
CDG55_RS06750 (CDG55_06750) 1122978..1124042 + 1065 WP_087537450.1 macro domain-containing protein Antitoxin
CDG55_RS06755 (CDG55_06755) 1124220..1127342 + 3123 WP_087537451.1 SIR2 family protein -
CDG55_RS06760 (CDG55_06760) 1127435..1128706 - 1272 WP_087537453.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(18-218)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 220 a.a.        Molecular weight: 25369.84 Da        Isoelectric Point: 6.0143

>T101456 WP_087537449.1 NZ_CP028561:1122322-1122981 [Acinetobacter sp. WCHA45]
MTEREYSESLNPQKALIWRIVHLDNIAWVLEHGLHCGNSLTASPNWVHIGNTELIDKRANHPVPVGQGGYLNDYVPFYFT
PFSPMLLNITTGRGGVRQRSNDEIVILVSSLHRLQELNMPFVFTDGHAYYQWSNFYTDLADLDKIDWQILQKKDFSRDVD
DPAKFERYQAEALVHQHCPIEALLGMICYNEKIKSLLEQQLQQANIEMPVYVRSGVYFK

Download         Length: 660 bp

>T101456 NZ_CP028561:1122322-1122981 [Acinetobacter sp. WCHA45]
ATGACAGAACGTGAGTATAGCGAATCTCTCAATCCACAAAAAGCATTGATCTGGAGAATTGTACATCTGGATAATATTGC
TTGGGTTTTGGAACATGGCTTGCACTGTGGCAATAGCCTTACGGCTTCCCCAAATTGGGTACATATTGGTAATACCGAAT
TAATTGATAAAAGAGCAAATCATCCTGTACCAGTTGGACAGGGTGGATACCTGAATGATTATGTACCTTTTTATTTTACG
CCATTTTCTCCCATGCTTTTGAACATCACAACAGGGCGAGGTGGTGTCCGACAGCGTTCTAATGATGAGATTGTCATTCT
CGTATCAAGTCTGCATCGTTTACAGGAATTGAATATGCCGTTTGTATTCACAGATGGTCATGCCTATTATCAATGGTCAA
ATTTCTATACGGATTTAGCTGATTTAGATAAGATTGATTGGCAGATTTTACAGAAAAAAGATTTCAGTCGGGATGTGGAT
GATCCCGCAAAGTTTGAACGTTATCAGGCAGAGGCACTTGTACATCAACATTGTCCGATTGAAGCCCTGCTCGGTATGAT
ATGTTACAATGAGAAAATTAAATCTTTGCTAGAGCAACAATTGCAGCAAGCAAATATTGAAATGCCTGTTTATGTAAGGT
CAGGAGTATATTTTAAATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 40155.14 Da        Isoelectric Point: 5.3205

>AT101456 WP_087537450.1 NZ_CP028561:1122978-1124042 [Acinetobacter sp. WCHA45]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMAAYRQACKEGRVQTGKMFVTETNEFLAPRWIVNFPTK
QHWKAKSQIEWVEDGLKDLKQFIIEKNISSIAIPPLGAGNGGLDWQDVKPKIESALSDLLDVDVLIFEPTEKYQNIAKNI
GVQKLTPARALIAELIRRYGVLGMECSILEIQKLAWFLQRVIEKHNLSNELRLDFQANYYGPYAHNLTHLLNALDGSYLK
SDKRIPDCEPLDVIWFNQQEQGKVQSYLNSEAKDFVPALEEAAALIEGFESPFGMELLSTVDWLIYKDGCQPTVESIKDG
LANWSAGKRWADRKLSLFKDEHIEYALDKLQKSI

Download         Length: 1065 bp

>AT101456 NZ_CP028561:1122978-1124042 [Acinetobacter sp. WCHA45]
ATGATTCGTTATACGACTGGAAACTTACTGGATGCCCCAGTAGAAGCATTGGTCAATACTGTAAATACAGTAGGGGTCAT
GGGGAAAGGCATTGCTTTGATGTTTAAAGAACGATTCCCTGACAATATGGCTGCCTATCGTCAAGCATGTAAAGAGGGGC
GTGTTCAAACAGGAAAAATGTTTGTTACAGAAACCAATGAATTTTTAGCACCTCGCTGGATCGTTAATTTTCCGACTAAA
CAACACTGGAAAGCCAAATCACAAATTGAATGGGTTGAAGATGGGCTGAAAGATTTAAAACAATTTATTATAGAAAAAAA
TATTTCATCTATTGCGATTCCGCCATTGGGTGCTGGTAATGGTGGGTTAGACTGGCAAGATGTAAAGCCAAAAATAGAAT
CTGCATTGTCAGATTTACTGGATGTGGATGTTCTAATTTTTGAACCGACTGAAAAATATCAGAATATTGCAAAAAATATT
GGTGTGCAAAAACTTACACCAGCTCGGGCTTTGATTGCAGAACTGATTCGTAGGTATGGGGTACTGGGTATGGAATGTAG
TATCCTTGAAATCCAAAAGTTAGCATGGTTTCTACAAAGAGTTATCGAAAAACATAATTTATCCAATGAGTTAAGATTGG
ATTTTCAGGCAAACTATTATGGTCCTTACGCCCACAATCTGACACATCTGCTTAATGCACTAGATGGCAGCTATTTAAAG
TCTGACAAAAGAATCCCTGATTGTGAACCATTGGATGTGATTTGGTTTAATCAACAGGAACAAGGCAAAGTACAAAGCTA
TTTGAACAGTGAGGCAAAAGATTTTGTGCCTGCTCTGGAAGAAGCGGCTGCTTTAATTGAGGGGTTTGAATCACCTTTTG
GAATGGAATTGCTTTCTACAGTAGATTGGCTGATCTATAAAGATGGATGTCAGCCAACGGTTGAATCTATTAAAGATGGG
TTAGCAAATTGGTCTGCTGGTAAACGCTGGGCAGATCGGAAGTTATCTTTATTTAAAGATGAACATATTGAGTATGCTTT
GGATAAGTTACAGAAGTCTATTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References