Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1866712..1867372 Replicon chromosome
Accession NZ_CP028520
Organism Lelliottia sp. WB101

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag DAI21_RS08930 Protein ID WP_100779036.1
Coordinates 1866959..1867372 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag DAI21_RS08925 Protein ID WP_095283258.1
Coordinates 1866712..1866978 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DAI21_RS08900 1861949..1863382 - 1434 WP_102104700.1 6-phospho-beta-glucosidase BglA -
DAI21_RS08905 1863499..1864230 - 732 WP_102104699.1 MurR/RpiR family transcriptional regulator -
DAI21_RS08910 1864283..1864594 + 312 WP_107702895.1 N(4)-acetylcytidine aminohydrolase -
DAI21_RS08915 1864758..1865417 + 660 WP_107702896.1 hemolysin III family protein -
DAI21_RS08920 1865464..1866444 - 981 WP_107702897.1 tRNA-modifying protein YgfZ -
DAI21_RS08925 1866712..1866978 + 267 WP_095283258.1 FAD assembly factor SdhE Antitoxin
DAI21_RS08930 1866959..1867372 + 414 WP_100779036.1 protein YgfX Toxin
DAI21_RS08935 1867377..1867898 - 522 WP_100779037.1 flavodoxin FldB -
DAI21_RS08940 1867999..1868895 + 897 WP_100779038.1 site-specific tyrosine recombinase XerD -
DAI21_RS08945 1868924..1869637 + 714 WP_107702898.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DAI21_RS08950 1869643..1871376 + 1734 WP_107702899.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16298.22 Da        Isoelectric Point: 11.2669

>T101352 WP_100779036.1 NZ_CP028520:1866959-1867372 [Lelliottia sp. WB101]
VVLWQSDLRVSWRSQWMSLLLHGIVAAFILLMPWPLSYTPLWMLLLSLVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEIVGTPWMLNSGMMFRLRKEEGARCQHLWLSADSMDASEWRDLRRMVMQQPTPGR

Download         Length: 414 bp

>T101352 NZ_CP028520:1866959-1867372 [Lelliottia sp. WB101]
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCGTGGCGCTCACAGTGGATGTCTCTTTTACTCCACGGCATTGTGGCGGC
TTTTATTTTGCTGATGCCGTGGCCGCTTAGCTATACACCGCTCTGGATGCTGCTTCTTTCGCTGGTGGTGTTCGACAGTG
TGCGCAGTCAGCGGCGTATCAACGCCCGTCAGGGTGAGATCAAACTGCTGATGGACTCGCGGTTGCGCTGGCAGGGCAAA
GAGTGGGAGATCGTCGGCACACCCTGGATGCTGAATTCCGGGATGATGTTCCGCCTGCGTAAAGAGGAAGGGGCGCGTTG
CCAGCATCTTTGGCTGTCAGCAGACAGTATGGATGCCAGCGAGTGGCGAGATTTGCGCCGGATGGTGATGCAGCAGCCGA
CGCCAGGACGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT101352 WP_095283258.1 NZ_CP028520:1866712-1866978 [Lelliottia sp. WB101]
MDINNKARIHWACRRGMRELDISVMPFFEYEYDSLSDDDKRLFIRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT101352 NZ_CP028520:1866712-1866978 [Lelliottia sp. WB101]
ATGGACATTAACAACAAGGCCCGTATCCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCGTCATGCCCTT
CTTCGAATATGAGTACGACAGCTTAAGCGATGATGATAAACGTCTGTTTATCCGCCTGCTGGAGAGTGACGATCCGGATT
TATTCAACTGGCTGATGAATCATGGCAAACCCGCCGACACCGAGTTGCAGCGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References