Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
| Location | 2244860..2245464 | Replicon | chromosome |
| Accession | NZ_CP028491 | ||
| Organism | Carboxydocella thermautotrophica strain 019 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | - |
| Locus tag | CFE_RS11315 | Protein ID | WP_078665312.1 |
| Coordinates | 2244860..2245210 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | - |
| Locus tag | CFE_RS11320 | Protein ID | WP_174183013.1 |
| Coordinates | 2245213..2245464 (-) | Length | 84 a.a. |
Genomic Context
Location: 2248580..2248954 (375 bp)
Type: Others
Protein ID: WP_078665316.1
Type: Others
Protein ID: WP_078665316.1
Location: 2240903..2241604 (702 bp)
Type: Others
Protein ID: WP_078665308.1
Type: Others
Protein ID: WP_078665308.1
Location: 2241618..2242553 (936 bp)
Type: Others
Protein ID: WP_078665309.1
Type: Others
Protein ID: WP_078665309.1
Location: 2242676..2244004 (1329 bp)
Type: Others
Protein ID: WP_078665310.1
Type: Others
Protein ID: WP_078665310.1
Location: 2244210..2244785 (576 bp)
Type: Others
Protein ID: WP_078665311.1
Type: Others
Protein ID: WP_078665311.1
Location: 2244860..2245210 (351 bp)
Type: Toxin
Protein ID: WP_078665312.1
Type: Toxin
Protein ID: WP_078665312.1
Location: 2245213..2245464 (252 bp)
Type: Antitoxin
Protein ID: WP_174183013.1
Type: Antitoxin
Protein ID: WP_174183013.1
Location: 2245619..2246851 (1233 bp)
Type: Others
Protein ID: WP_078665314.1
Type: Others
Protein ID: WP_078665314.1
Location: 2246991..2248370 (1380 bp)
Type: Others
Protein ID: WP_078665315.1
Type: Others
Protein ID: WP_078665315.1
Location: 2248999..2249736 (738 bp)
Type: Others
Protein ID: WP_078665317.1
Type: Others
Protein ID: WP_078665317.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CFE_RS11295 | 2240903..2241604 | - | 702 | WP_078665308.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| CFE_RS11300 | 2241618..2242553 | - | 936 | WP_078665309.1 | hypothetical protein | - |
| CFE_RS11305 | 2242676..2244004 | - | 1329 | WP_078665310.1 | type I glutamate--ammonia ligase | - |
| CFE_RS11310 | 2244210..2244785 | - | 576 | WP_078665311.1 | ANTAR domain-containing protein | - |
| CFE_RS11315 | 2244860..2245210 | - | 351 | WP_078665312.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| CFE_RS11320 | 2245213..2245464 | - | 252 | WP_174183013.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
| CFE_RS11325 | 2245619..2246851 | - | 1233 | WP_078665314.1 | transposase | - |
| CFE_RS11330 | 2246991..2248370 | - | 1380 | WP_078665315.1 | dihydrolipoyl dehydrogenase | - |
| CFE_RS11335 | 2248580..2248954 | + | 375 | WP_078665316.1 | hypothetical protein | - |
| CFE_RS11340 | 2248999..2249736 | - | 738 | WP_078665317.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12816.84 Da Isoelectric Point: 7.2058
>T101348 WP_078665312.1 NZ_CP028491:c2245210-2244860 [Carboxydocella thermautotrophica]
MRIRRGDIFYAELSPVVGSEQGGTRPVLVLQNDIGNQHSPTTIVAAITSQISKAKLPTHVEIKAKISGLEKDSVILLEQI
RTIDKSRLREKVSTLDEEIMEKVNRAIAISLGLEEI
MRIRRGDIFYAELSPVVGSEQGGTRPVLVLQNDIGNQHSPTTIVAAITSQISKAKLPTHVEIKAKISGLEKDSVILLEQI
RTIDKSRLREKVSTLDEEIMEKVNRAIAISLGLEEI
Download Length: 351 bp
>T101348 NZ_CP028491:c2245210-2244860 [Carboxydocella thermautotrophica]
ATGCGGATTCGCCGCGGTGATATCTTTTACGCAGAGCTTAGCCCGGTGGTGGGCTCAGAACAGGGCGGAACTCGACCAGT
TCTGGTCCTGCAAAATGATATTGGCAACCAGCATAGTCCCACCACCATAGTGGCGGCCATTACTTCCCAGATCAGTAAAG
CCAAACTCCCCACCCATGTGGAGATTAAAGCTAAAATCAGCGGTCTGGAAAAGGATTCTGTGATATTGCTGGAACAGATT
CGCACCATCGATAAAAGCCGGCTGAGGGAGAAAGTTAGTACTCTGGATGAGGAGATCATGGAAAAAGTTAACCGGGCTAT
TGCTATCAGCCTGGGGTTGGAAGAAATATAG
ATGCGGATTCGCCGCGGTGATATCTTTTACGCAGAGCTTAGCCCGGTGGTGGGCTCAGAACAGGGCGGAACTCGACCAGT
TCTGGTCCTGCAAAATGATATTGGCAACCAGCATAGTCCCACCACCATAGTGGCGGCCATTACTTCCCAGATCAGTAAAG
CCAAACTCCCCACCCATGTGGAGATTAAAGCTAAAATCAGCGGTCTGGAAAAGGATTCTGTGATATTGCTGGAACAGATT
CGCACCATCGATAAAAGCCGGCTGAGGGAGAAAGTTAGTACTCTGGATGAGGAGATCATGGAAAAAGTTAACCGGGCTAT
TGCTATCAGCCTGGGGTTGGAAGAAATATAG
Antitoxin
Download Length: 84 a.a. Molecular weight: 9476.89 Da Isoelectric Point: 4.5960
>AT101348 WP_174183013.1 NZ_CP028491:c2245464-2245213 [Carboxydocella thermautotrophica]
MISLPDQLLAEVDGLASAEKLNRSQLFREAVQHYIAERKKRQIREQMIRGYMEMAPINLSLANEYMGLEVDGTLPLWQAA
EGE
MISLPDQLLAEVDGLASAEKLNRSQLFREAVQHYIAERKKRQIREQMIRGYMEMAPINLSLANEYMGLEVDGTLPLWQAA
EGE
Download Length: 252 bp
>AT101348 NZ_CP028491:c2245464-2245213 [Carboxydocella thermautotrophica]
ATGATCAGCCTGCCCGATCAATTGCTGGCTGAGGTGGATGGTCTGGCTTCAGCGGAAAAACTGAACCGCAGCCAGTTATT
TCGTGAAGCTGTCCAGCACTATATAGCAGAACGAAAAAAACGGCAGATCAGGGAGCAAATGATCCGCGGCTATATGGAAA
TGGCCCCGATTAACCTGTCTCTGGCTAACGAGTATATGGGCCTGGAGGTCGATGGAACCCTTCCCCTGTGGCAAGCGGCA
GAGGGGGAATAA
ATGATCAGCCTGCCCGATCAATTGCTGGCTGAGGTGGATGGTCTGGCTTCAGCGGAAAAACTGAACCGCAGCCAGTTATT
TCGTGAAGCTGTCCAGCACTATATAGCAGAACGAAAAAAACGGCAGATCAGGGAGCAAATGATCCGCGGCTATATGGAAA
TGGCCCCGATTAACCTGTCTCTGGCTAACGAGTATATGGGCCTGGAGGTCGATGGAACCCTTCCCCTGTGGCAAGCGGCA
GAGGGGGAATAA