Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 2395977..2396490 Replicon chromosome
Accession NZ_CP028490
Organism Pseudomonas syringae pv. atrofaciens strain LMG5095 isolate Triticum aestivum (Aestivum Group)

Toxin (Protein)


Gene name relE Uniprot ID A0A0P9GC66
Locus tag DA456_RS10140 Protein ID WP_003423365.1
Coordinates 2396206..2396490 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0P9IXK3
Locus tag DA456_RS10135 Protein ID WP_004418474.1
Coordinates 2395977..2396216 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA456_RS10115 2392091..2392876 + 786 WP_003423373.1 membrane protein -
DA456_RS10120 2393053..2393961 - 909 WP_024664322.1 DUF808 domain-containing protein -
DA456_RS10125 2394108..2394614 - 507 WP_003315203.1 Lrp/AsnC family transcriptional regulator -
DA456_RS10130 2394801..2395817 + 1017 WP_003423368.1 1-aminocyclopropane-1-carboxylate deaminase -
DA456_RS10135 2395977..2396216 + 240 WP_004418474.1 CopG family ribbon-helix-helix protein Antitoxin
DA456_RS10140 2396206..2396490 + 285 WP_003423365.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DA456_RS10145 2396525..2397379 - 855 WP_029572166.1 LysR family transcriptional regulator -
DA456_RS10150 2397454..2398386 + 933 WP_029572165.1 DMT family transporter -
DA456_RS10155 2398420..2400348 - 1929 WP_029572164.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10632.34 Da        Isoelectric Point: 10.4249

>T101345 WP_003423365.1 NZ_CP028490:2396206-2396490 [Pseudomonas syringae pv. atrofaciens]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Download         Length: 285 bp

>T101345 NZ_CP028490:2396206-2396490 [Pseudomonas syringae pv. atrofaciens]
ATGCAGGTTGAGTGGCTCAAAACAGCACTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACTGGACAATCCAGCTGC
TGCCGCTGCTTTCGTGAAAGCCATTCAATCAAGCGTAACGCAGCTCGCTAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGACTACAGGTT
CTACGGATTTTCCACACCAGAAGACAATCGCCACCCGTGTGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8670.76 Da        Isoelectric Point: 4.4217

>AT101345 WP_004418474.1 NZ_CP028490:2395977-2396216 [Pseudomonas syringae pv. atrofaciens]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASPDDVKAVMDKWSGNAG

Download         Length: 240 bp

>AT101345 NZ_CP028490:2395977-2396216 [Pseudomonas syringae pv. atrofaciens]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCAGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACACGCGAGGCTTGGCAGATTGCCGAAATTCAGCGTGCCATCG
AAGAAGCCGACGCCGGCGAGTTCGCAAGCCCAGACGACGTAAAAGCTGTCATGGACAAATGGTCAGGCAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9GC66

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9IXK3

References