Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 971943..972615 Replicon chromosome
Accession NZ_CP028487
Organism Yersinia massiliensis strain GTA

Toxin (Protein)


Gene name cptA Uniprot ID A0A0T9UGW4
Locus tag DA391_RS04420 Protein ID WP_050082213.1
Coordinates 972190..972615 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A0T9UGT3
Locus tag DA391_RS04415 Protein ID WP_019211617.1
Coordinates 971943..972209 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA391_RS04400 968931..969680 + 750 WP_050286433.1 SDR family oxidoreductase -
DA391_RS04405 969925..970617 + 693 WP_050082335.1 hemolysin III family protein -
DA391_RS04410 970702..971691 - 990 WP_108087409.1 tRNA-modifying protein YgfZ -
DA391_RS04415 971943..972209 + 267 WP_019211617.1 FAD assembly factor SdhE Antitoxin
DA391_RS04420 972190..972615 + 426 WP_050082213.1 protein YgfX Toxin
DA391_RS04425 972615..973313 + 699 WP_050286436.1 two-component system response regulator CreB -
DA391_RS04430 973352..974779 + 1428 WP_050286437.1 two-component system sensor histidine kinase CreC -
DA391_RS04435 974871..976295 + 1425 WP_050082216.1 cell envelope integrity protein CreD -
DA391_RS04440 976386..976904 - 519 WP_050286440.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16527.43 Da        Isoelectric Point: 9.4189

>T101326 WP_050082213.1 NZ_CP028487:972190-972615 [Yersinia massiliensis]
VAQWRCDLRISWHTQLFSLLTHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNITSCQGEIRLKPGNVVLWKRL
EWIVVKQPWMTRYGVLLRLRQANSRSTCKRLWLAADSMSEDEWRQLCLLLRHSFDADEGHT

Download         Length: 426 bp

>T101326 NZ_CP028487:972190-972615 [Yersinia massiliensis]
GTGGCCCAGTGGCGATGTGACCTACGTATATCCTGGCACACTCAACTTTTCTCTTTATTGACACATGGTGTCTTGGTCAT
ACTCACGCTGGTCGCACCCTGGCCTCAGGGTTATACCGCGCTGTGGTTAGTATTACTGACGCTGGTAGTCTTTGAGTGTA
TCCGCAGCCAGAAGAATATTACCTCCTGCCAAGGGGAGATCAGGCTGAAACCCGGCAATGTGGTGCTATGGAAACGGCTT
GAATGGATTGTCGTTAAGCAGCCATGGATGACCCGATATGGCGTGTTATTGCGCTTACGGCAGGCAAACAGTCGATCAAC
CTGTAAGCGCCTATGGCTGGCGGCTGATAGCATGTCAGAAGATGAGTGGCGGCAACTTTGCTTGCTATTGCGTCACTCCT
TTGATGCGGATGAAGGGCATACCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.06 Da        Isoelectric Point: 4.6786

>AT101326 WP_019211617.1 NZ_CP028487:971943-972209 [Yersinia massiliensis]
MEIDNKARIHWACRRGMRELDISIMPFFEYEYDGLSDSEKQIFIRLLECDDPDLFNWLMNHGEPQDDELRQMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT101326 NZ_CP028487:971943-972209 [Yersinia massiliensis]
ATGGAAATCGATAATAAAGCCCGTATTCACTGGGCATGCCGCCGTGGTATGCGTGAACTGGATATCTCCATCATGCCATT
TTTTGAATACGAATATGATGGCTTGAGTGATAGCGAGAAGCAGATTTTTATTCGGCTACTGGAATGTGATGACCCAGACC
TTTTCAATTGGCTGATGAATCATGGGGAGCCGCAGGATGACGAACTGCGTCAGATGGTGAAATTGATTCAAACGCGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0T9UGW4

Antitoxin

Source ID Structure
AlphaFold DB A0A0T9UGT3

References