Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2175765..2176033 Replicon chromosome
Accession NZ_CP028483
Organism Escherichia coli strain E41-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2175893..2175995 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2175765..2176033 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2U19_RS11055 2172318..2172980 - 663 WP_000944256.1 exodeoxyribonuclease X -
C2U19_RS11060 2173004..2173660 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
C2U19_RS11065 2173762..2173992 - 231 WP_000916763.1 DNA polymerase III subunit theta -
C2U19_RS11070 2174131..2174505 + 375 WP_000168747.1 CopC domain-containing protein YobA -
C2U19_RS11075 2174509..2175381 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
C2U19_RS11080 2175394..2175735 + 342 WP_000976472.1 YebY family protein -
- 2175765..2176033 - 269 - - Antitoxin
- 2175893..2175995 + 103 - - Toxin
C2U19_RS11085 2176130..2176786 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
C2U19_RS11090 2176787..2176978 - 192 WP_001296140.1 YebW family protein -
C2U19_RS11095 2177083..2177319 - 237 WP_001295499.1 DUF1480 family protein -
C2U19_RS11100 2177436..2178875 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T101291 NZ_CP028483:2175893-2175995 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT101291 NZ_CP028483:c2176033-2175765 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References