Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafN(antitoxin)
Location 1943522..1944087 Replicon chromosome
Accession NZ_CP028481
Organism Vibrio parahaemolyticus strain S107-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DA442_RS09565 Protein ID WP_134990595.1
Coordinates 1943522..1943809 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DA442_RS09570 Protein ID WP_023667330.1
Coordinates 1943806..1944087 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA442_RS09510 1939160..1939426 - 267 WP_005464625.1 hypothetical protein -
DA442_RS25970 1939597..1939764 - 168 WP_001883086.1 DUF3265 domain-containing protein -
DA442_RS09525 1940200..1940505 - 306 WP_025639377.1 hypothetical protein -
DA442_RS09530 1940608..1941147 - 540 WP_031846516.1 hypothetical protein -
DA442_RS09535 1941137..1942102 - 966 WP_031846517.1 hypothetical protein -
DA442_RS09540 1942206..1942298 - 93 WP_078532100.1 DUF3265 domain-containing protein -
DA442_RS09545 1942341..1942715 - 375 WP_134990594.1 hypothetical protein -
DA442_RS26100 1942758..1942850 - 93 WP_071936844.1 DUF3265 domain-containing protein -
DA442_RS09555 1942876..1943355 - 480 WP_047726353.1 hypothetical protein -
DA442_RS09560 1943403..1943519 - 117 WP_078532102.1 DUF3265 domain-containing protein -
DA442_RS09565 1943522..1943809 - 288 WP_134990595.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DA442_RS09570 1943806..1944087 - 282 WP_023667330.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DA442_RS09575 1944178..1944309 - 132 WP_005494795.1 DUF3265 domain-containing protein -
DA442_RS09585 1944779..1944907 - 129 WP_079771076.1 DUF3265 domain-containing protein -
DA442_RS09590 1945006..1945590 + 585 WP_064484278.1 hypothetical protein -
DA442_RS09595 1945643..1945735 - 93 WP_005433818.1 DUF3265 domain-containing protein -
DA442_RS09600 1945750..1946496 - 747 WP_050549766.1 hypothetical protein -
DA442_RS09605 1946659..1948131 - 1473 WP_134990596.1 AAA family ATPase -
DA442_RS09610 1948169..1948258 - 90 WP_079771093.1 DUF3265 domain-containing protein -
DA442_RS09620 1948780..1948869 - 90 WP_079771094.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1918267..2031908 113641


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10979.56 Da        Isoelectric Point: 5.0980

>T101279 WP_134990595.1 NZ_CP028481:c1943809-1943522 [Vibrio parahaemolyticus]
MKVVWSPLALQKLGDAAEFISLDNPSATEKWVNDVFDKTESLGSMPEMGRFVPEIPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILTEDDV

Download         Length: 288 bp

>T101279 NZ_CP028481:c1943809-1943522 [Vibrio parahaemolyticus]
ATGAAAGTAGTTTGGTCTCCTTTGGCTCTTCAAAAGCTTGGTGATGCTGCTGAATTTATTTCACTAGACAATCCGTCTGC
TACTGAAAAGTGGGTAAATGACGTTTTCGATAAAACTGAATCACTCGGAAGTATGCCTGAAATGGGGCGCTTTGTTCCTG
AAATACCCCATACAAACTATCGTGAAATCATTTTCGGTCACTATCGTATTATTTATAGTTTAAGCCACGAAATTCGTGTG
TTAACAGTTCGTAATTGTCGTCAGATTTTGACGGAAGATGACGTGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10427.94 Da        Isoelectric Point: 5.1991

>AT101279 WP_023667330.1 NZ_CP028481:c1944087-1943806 [Vibrio parahaemolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
EEARAEVLGRIKK

Download         Length: 282 bp

>AT101279 NZ_CP028481:c1944087-1943806 [Vibrio parahaemolyticus]
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCGCTATCTGAGTTTCGTGCCGGTGTAGCTTCTTACATCAAACAAAT
CAATGAGACTCGTCGTCCGTTGGTAATTACACAACGCGGTAAAGGTGTTGCTGTTGTTCTTGATGTTGCGGAGTATGAAG
CAATGCAAGAGAAAATCGAGTTACTGGAAGAAATGCGCACAGCAGAAGCTCAATTAGCTTCAGGTCTTGGTGTTTCAAAT
GAAGAAGCGCGCGCTGAGGTTTTAGGGCGCATTAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References