Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1931520..1932079 Replicon chromosome
Accession NZ_CP028481
Organism Vibrio parahaemolyticus strain S107-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DA442_RS09440 Protein ID WP_031846599.1
Coordinates 1931801..1932079 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DA442_RS09435 Protein ID WP_031846598.1
Coordinates 1931520..1931804 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DA442_RS09375 1926626..1926706 - 81 WP_078532227.1 DUF3265 domain-containing protein -
DA442_RS09380 1926721..1927143 - 423 WP_025523873.1 hypothetical protein -
DA442_RS09385 1927291..1928175 - 885 WP_031778322.1 hypothetical protein -
DA442_RS09395 1928691..1928813 - 123 WP_078532228.1 DUF3265 domain-containing protein -
DA442_RS25960 1929175..1929342 - 168 WP_001883086.1 DUF3265 domain-containing protein -
DA442_RS26095 1929615..1929707 - 93 WP_079386106.1 DUF3265 domain-containing protein -
DA442_RS09420 1929722..1930279 - 558 WP_029857376.1 hypothetical protein -
DA442_RS09425 1930306..1930398 - 93 WP_072612521.1 DUF3265 domain-containing protein -
DA442_RS09430 1930425..1930832 - 408 WP_134990591.1 SH3 domain-containing protein -
DA442_RS09435 1931520..1931804 + 285 WP_031846598.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DA442_RS09440 1931801..1932079 + 279 WP_031846599.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
DA442_RS09445 1932108..1932200 - 93 WP_079766442.1 DUF3265 domain-containing protein -
DA442_RS09450 1932215..1932568 - 354 WP_031829440.1 hypothetical protein -
DA442_RS09460 1932741..1933496 - 756 WP_006741457.1 DUF3944 domain-containing protein -
DA442_RS09465 1933718..1935271 - 1554 WP_031778359.1 DUF4263 domain-containing protein -
DA442_RS09470 1935503..1935769 - 267 WP_025527397.1 barstar family protein -
DA442_RS09475 1935800..1935922 - 123 Protein_1723 DUF3265 domain-containing protein -
DA442_RS09485 1936285..1936374 - 90 WP_078231742.1 DUF3265 domain-containing protein -
DA442_RS09490 1936392..1936700 - 309 WP_031846389.1 hypothetical protein -
DA442_RS09495 1936745..1936837 - 93 WP_202817082.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1918267..2031908 113641


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-45)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10935.69 Da        Isoelectric Point: 4.3324

>T101278 WP_031846599.1 NZ_CP028481:1931801-1932079 [Vibrio parahaemolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPDISMIVSYWIEGDIIRIM
RVLHQKQKFPMD

Download         Length: 279 bp

>T101278 NZ_CP028481:1931801-1932079 [Vibrio parahaemolyticus]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAGAAAACTGACAACCTCATTGAAGCAAAAGTGGAGAACTTGCTAGAGCAGCCACTAATGGGTGTGCAGCGAGATGGTA
TTCGTGGGCGATTACTTATAATCCCTGATATTTCAATGATCGTCTCCTATTGGATCGAAGGCGACATTATCCGAATCATG
CGCGTGCTTCACCAGAAACAAAAATTTCCTATGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11055.37 Da        Isoelectric Point: 9.2167

>AT101278 WP_031846598.1 NZ_CP028481:1931520-1931804 [Vibrio parahaemolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVDHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT101278 NZ_CP028481:1931520-1931804 [Vibrio parahaemolyticus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTAAGTGACGCATGCCGTGAACTTACTGAGCAACTCGCTGAGCAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGACCACCAAACTGCTAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References