Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2280431..2280702 Replicon chromosome
Accession NZ_CP028432
Organism Escherichia coli strain RM9975

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2280469..2280572 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2280431..2280702 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECRM9975_RS12305 2277588..2279027 + 1440 WP_000057021.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ECRM9975_RS12310 2279145..2279381 + 237 WP_001295499.1 DUF1480 family protein -
ECRM9975_RS12315 2279486..2279677 + 192 WP_001296140.1 YebW family protein -
ECRM9975_RS12320 2279678..2280334 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2280431..2280702 + 272 - - Antitoxin
- 2280469..2280572 - 104 - - Toxin
ECRM9975_RS12325 2280730..2281071 - 342 WP_000976492.1 YebY family protein -
ECRM9975_RS12330 2281084..2281956 - 873 WP_000879274.1 copper homeostasis membrane protein CopD -
ECRM9975_RS12335 2281960..2282334 - 375 WP_000204699.1 CopC domain-containing protein YobA -
ECRM9975_RS12340 2282473..2282703 + 231 WP_000916763.1 DNA polymerase III subunit theta -
ECRM9975_RS12345 2282805..2283461 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
ECRM9975_RS12350 2283485..2284147 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T101195 NZ_CP028432:c2280572-2280469 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT101195 NZ_CP028432:2280431-2280702 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References