Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2004014..2004159 Replicon chromosome
Accession NZ_CP028391
Organism Klebsiella pneumoniae strain WCHKP13F2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2004050..2004152 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2004014..2004159 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7D34_RS12190 1999144..2001204 + 2061 WP_004151449.1 oligopeptidase B -
B7D34_RS12195 2001208..2001867 - 660 WP_002911407.1 exodeoxyribonuclease X -
B7D34_RS12200 2001946..2002176 - 231 WP_002911406.1 DNA polymerase III subunit theta -
B7D34_RS12205 2002289..2002663 + 375 WP_004151448.1 CopC domain-containing protein YobA -
B7D34_RS12210 2002667..2003536 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
B7D34_RS12215 2003550..2003891 + 342 WP_015874944.1 YebY family protein -
- 2004014..2004159 - 146 - - Antitoxin
- 2004050..2004152 + 103 - - Toxin
B7D34_RS12220 2004194..2004385 - 192 WP_004175432.1 hypothetical protein -
B7D34_RS12225 2004775..2005665 - 891 WP_085388938.1 VirK/YbjX family protein -
B7D34_RS12230 2005900..2006553 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
B7D34_RS12235 2006550..2006741 - 192 WP_002911395.1 YebW family protein -
B7D34_RS12240 2006839..2007078 - 240 WP_002911393.1 YebV family protein -
B7D34_RS12245 2007194..2008627 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T101127 NZ_CP028391:2004050-2004152 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT101127 NZ_CP028391:c2004159-2004014 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References