Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 882596..883134 Replicon chromosome
Accession NZ_CP028384
Organism Providencia heimbachae strain 99101

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C9446_RS03795 Protein ID WP_137021258.1
Coordinates 882844..883134 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C9446_RS03790 Protein ID WP_137021257.1
Coordinates 882596..882847 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9446_RS03770 877925..879001 + 1077 WP_068909472.1 class II fructose-bisphosphate aldolase -
C9446_RS03775 879086..879946 - 861 WP_137021254.1 LysR family transcriptional regulator -
C9446_RS03780 880232..881458 + 1227 WP_137021255.1 sodium:glutamate symporter -
C9446_RS03785 881501..882466 + 966 WP_137021256.1 agmatinase -
C9446_RS03790 882596..882847 + 252 WP_137021257.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C9446_RS03795 882844..883134 + 291 WP_137021258.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C9446_RS03800 883129..883494 - 366 WP_137021259.1 DUF4440 domain-containing protein -
C9446_RS03805 883494..884363 - 870 WP_082913034.1 LysR family transcriptional regulator -
C9446_RS03810 884429..885115 + 687 WP_068439413.1 ankyrin repeat domain-containing protein -
C9446_RS03815 885115..885579 + 465 WP_068909475.1 nucleoside deaminase -
C9446_RS03820 885579..886763 + 1185 WP_137021260.1 cyanate transporter -
C9446_RS03825 886956..887588 - 633 WP_068909480.1 fimbrial protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11079.01 Da        Isoelectric Point: 10.2746

>T101109 WP_137021258.1 NZ_CP028384:882844-883134 [Providencia heimbachae]
MNDSYSIKFRDDAVKEWKKLGVTVQRQFAKKLKSLIENPHIPSAKLGGLPNCYKIKLKASGYRLVYEVIDNELIIIVITV
GKRNRNEVYDIAKDRL

Download         Length: 291 bp

>T101109 NZ_CP028384:882844-883134 [Providencia heimbachae]
ATGAATGATAGCTACAGCATTAAGTTCAGGGATGATGCAGTAAAAGAGTGGAAAAAATTGGGGGTAACAGTACAAAGGCA
ATTTGCGAAAAAATTAAAATCGTTGATAGAAAACCCGCATATTCCATCGGCAAAGCTGGGTGGCTTGCCCAATTGCTATA
AAATCAAATTAAAGGCATCTGGTTATCGACTTGTTTATGAGGTGATTGATAATGAGCTAATTATTATCGTAATTACCGTT
GGGAAAAGAAATCGTAACGAAGTCTATGACATTGCTAAAGATAGGTTATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9308.68 Da        Isoelectric Point: 4.1546

>AT101109 WP_137021257.1 NZ_CP028384:882596-882847 [Providencia heimbachae]
MPQVILSDVTASISELKKNPMATVDSGEGFPVAILNRNKPAFYCVPADVYENLLEQIEDKELIEIVKARQNQKLVDIDLD
SYL

Download         Length: 252 bp

>AT101109 NZ_CP028384:882596-882847 [Providencia heimbachae]
ATGCCACAGGTTATCCTAAGTGATGTGACTGCAAGTATTAGTGAATTAAAAAAGAACCCGATGGCAACAGTTGATTCTGG
CGAAGGTTTTCCTGTTGCAATACTGAATAGAAATAAGCCTGCATTTTATTGTGTTCCGGCAGATGTTTATGAGAATTTAC
TGGAACAAATAGAAGATAAAGAACTGATTGAAATTGTTAAAGCTAGGCAGAATCAGAAATTAGTCGATATTGATTTGGAT
AGCTATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References