Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2333915..2334183 Replicon chromosome
Accession NZ_CP028379
Organism Escherichia coli O145 str. RM9872

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2333953..2334056 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2333915..2334183 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I3Y_RS12180 2331072..2332511 + 1440 WP_024221588.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I3Y_RS12185 2332629..2332865 + 237 WP_001295499.1 DUF1480 family protein -
I3Y_RS12190 2332970..2333161 + 192 WP_001313035.1 YebW family protein -
I3Y_RS12195 2333162..2333818 - 657 WP_000812714.1 protein-serine/threonine phosphatase -
- 2333915..2334183 + 269 - - Antitoxin
- 2333953..2334056 - 104 - - Toxin
I3Y_RS12200 2334213..2334554 - 342 WP_000976475.1 YebY family protein -
I3Y_RS12205 2334567..2335439 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
I3Y_RS12210 2335443..2335817 - 375 WP_000168738.1 CopC domain-containing protein YobA -
I3Y_RS12215 2335956..2336186 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I3Y_RS12220 2336288..2336944 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
I3Y_RS12225 2336968..2337630 + 663 WP_000944252.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T101058 NZ_CP028379:c2334056-2333953 [Escherichia coli O145 str. RM9872]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT101058 NZ_CP028379:2333915-2334183 [Escherichia coli O145 str. RM9872]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References