Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 307884..308506 Replicon chromosome
Accession NZ_CP028358
Organism Stenotrophomonas maltophilia strain W18

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C9J74_RS01385 Protein ID WP_049431373.1
Coordinates 308216..308506 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C9J74_RS01380 Protein ID WP_197596373.1
Coordinates 307884..308168 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J74_RS01350 302996..303793 + 798 WP_107378945.1 enoyl-CoA hydratase -
C9J74_RS01355 303790..304965 + 1176 WP_107378946.1 enoyl-CoA hydratase/isomerase family protein -
C9J74_RS01360 304962..305852 + 891 WP_107378947.1 3-hydroxyisobutyrate dehydrogenase -
C9J74_RS01365 306081..306506 - 426 WP_004153735.1 organic hydroperoxide resistance protein -
C9J74_RS01370 306618..307598 - 981 WP_049448197.1 cation transporter -
C9J74_RS01380 307884..308168 - 285 WP_197596373.1 putative addiction module antidote protein Antitoxin
C9J74_RS01385 308216..308506 - 291 WP_049431373.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C9J74_RS01390 308652..310433 - 1782 WP_049448200.1 peptidoglycan-binding protein -
C9J74_RS01395 310476..310907 - 432 WP_049448202.1 DUF1311 domain-containing protein -
C9J74_RS01400 311146..312009 + 864 WP_159054928.1 DUF1311 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-94)

Antitoxin

Uncharacterized protein HI1420

(14-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10850.47 Da        Isoelectric Point: 11.8946

>T101030 WP_049431373.1 NZ_CP028358:c308506-308216 [Stenotrophomonas maltophilia]
MAILQATETFTRWLRGLNDSRARGVIVERLQRVARGLEGDVRSVGHGVSELRINHGPGYRVYFTRRGRSIVVLLHGGDKS
SQRRDIEKAVRLAELL

Download         Length: 291 bp

>T101030 NZ_CP028358:c308506-308216 [Stenotrophomonas maltophilia]
ATGGCGATTCTCCAGGCAACAGAGACATTCACGCGATGGCTGCGTGGACTCAACGACAGCAGGGCCCGCGGCGTGATCGT
GGAGCGCCTGCAGCGCGTCGCCCGCGGTCTCGAGGGAGATGTCCGATCAGTGGGTCATGGCGTAAGCGAACTGCGAATCA
ACCATGGGCCGGGATATCGCGTGTATTTCACACGTCGTGGGAGATCCATCGTCGTGCTCCTGCACGGTGGCGACAAGTCG
AGCCAGCGTCGCGATATCGAAAAAGCGGTCAGGCTCGCGGAGCTGCTGTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9809.11 Da        Isoelectric Point: 6.2105

>AT101030 WP_197596373.1 NZ_CP028358:c308168-307884 [Stenotrophomonas maltophilia]
MKTIPFDPADYLDDDVAIATYLSEALAAGDAGHFQEALGTVARARGMGGVAEVSGLGRESLYKALRPGAHPRFDTVQRVL
SALGVHLTVQAGKA

Download         Length: 285 bp

>AT101030 NZ_CP028358:c308168-307884 [Stenotrophomonas maltophilia]
CTGAAGACAATTCCCTTCGATCCCGCAGACTATCTGGATGATGACGTCGCAATCGCCACCTATCTAAGCGAGGCGTTGGC
AGCAGGTGACGCGGGCCACTTCCAGGAGGCACTCGGAACAGTGGCGCGCGCCCGCGGCATGGGCGGCGTTGCCGAGGTCT
CCGGCCTGGGACGCGAAAGCCTGTACAAGGCGCTGCGCCCCGGAGCACACCCACGCTTCGATACCGTGCAACGTGTGCTG
TCGGCGCTTGGGGTGCATCTGACCGTGCAGGCCGGTAAGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References