Detailed information of TA system TA101028

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 3211693..3213409
• Replicon: chromosome
• Accession: NZ_CP028355
• Organism: Shewanella baltica strain CW2

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: C8I07_RS13940
• Protein ID: WP_107404059.1
• Coordinates: 3212474..3213409 (+)
• Length: 312 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: -
• Locus tag: C8I07_RS13935
• Protein ID: WP_107404058.1
• Coordinates: 3211693..3212481 (+)
• Length: 263 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C8I07_RS13905	3206867..3207274	+	408	WP_107404054.1	peptidase	-
C8I07_RS13910	3207274..3208530	+	1257	WP_107404055.1	Y-family DNA polymerase	-
C8I07_RS13920	3209189..3210190	+	1002	WP_107404056.1	hypothetical protein	-
C8I07_RS13925	3210413..3210793	+	381	WP_107404057.1	DUF952 domain-containing protein	-
C8I07_RS13930	3211040..3211438	-	399	WP_012089073.1	hypothetical protein	-
C8I07_RS13935	3211693..3212481	+	789	WP_107404058.1	type IV toxin-antitoxin system AbiEi family antitoxin	Antitoxin
C8I07_RS13940	3212474..3213409	+	936	WP_107404059.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
C8I07_RS13945	3213529..3213939	-	411	WP_107404060.1	hypothetical protein	-
C8I07_RS13950	3213976..3214236	-	261	WP_107404061.1	hypothetical protein	-
C8I07_RS13955	3214354..3215814	-	1461	WP_107404062.1	site-specific integrase	-
C8I07_RS13960	3216002..3216388	+	387	WP_107404063.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	3190920..3216918	25998

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (13-266)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-97)

Sequences

Toxin

Protein

• Length: 312 a.a.
• Molecular weight: 35331.12 Da
• Isoelectric Point: 6.7660

>T101028 WP_107404059.1 NZ_CP028355:3212474-3213409 [Shewanella baltica]
MNKSSIYYQQVTLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAQINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGISREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLDELVLTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSVAALPAVRWKLLNIQNLAKNKSKHQEQLIKLADVLETWVAGRIL

Nucleotide

• Length: 936 bp

>T101028 NZ_CP028355:3212474-3213409 [Shewanella baltica]
ATGAATAAGTCATCGATATACTACCAGCAAGTGACGTTGCTTATTCGGATGCTGCCGCTCGTCGCCCAAGAGAAGGTATT
TGCTCTAAAGGGCGGTACGGCTATCAACCTATTTGTGCGCAACTTCCCACGCTTATCGGTCGATATCGATTTGGCTTATC
TTCCTTTGGAGCCAAGGGAACAAGCGCTACAAAGTGTGAAGGAAGCGCTTGGTCGTTTGACTGCGCAGATCAATCTACAA
CCGAACCTTAGTGCAGTATTTCAAGACAATAAATATGATGAGCTCAGGGTTGTCGTGACAAGTGATAGGGTGACAATAAA
AATTGAAGTCTCTCCTGTTGCGAGAGGTACGCTACACAAAGCGGTATTAATGCCAGTCGTTGAGTTAGTTGAAGAGGAAT
TTGGGTATGCAGAGATCCCCGTTGTAAGCCTGCCTGATCTATACGGTGGTAAGTTATGTGCAGCGATGGATAGGCAGCAC
CCAAGGGATCTATTCGATGTGAAAATGCTGCTGGCGGAAGAGGGGATCAGTCGAGAGATTTTAGTCGGCTTTCTCACTTA
TACACTTAGCCATCCAAGACCCATTAATGAAGTGATGTCTCCACGTTGGAAACCGCTTGATGAAAGCTTTCAAACTGAAT
TCAATGGAATGACGACAAAGCCGATTAAACTCGATGAGCTGGTATTAACTCGCTCAGAAATGCTAACAGCGTTGCAGCAT
CACTTTACCGCAAAGGACAGAGATTTTTTATTATCCTTTAAACAGGGTCAGCCTGATTGGTCATTGTTTGATGAACCGAG
CGTTGCGGCACTACCTGCGGTGAGATGGAAGTTATTGAATATCCAAAACCTAGCGAAAAATAAATCCAAGCATCAAGAGC
AACTCATTAAACTGGCTGATGTATTGGAGACGTGGGTTGCAGGTCGGATACTGTAA

Antitoxin

Protein

• Length: 263 a.a.
• Molecular weight: 29865.01 Da
• Isoelectric Point: 9.6409

>AT101028 WP_107404058.1 NZ_CP028355:3211693-3212481 [Shewanella baltica]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPESTGKLQPHWVEALKAVNEQLKLPVHL
AGVSSLTYQGLSHYLQLSSEQVWVGCQSKQALPKWFRELEAQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRKIQSILNRSEAVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDGRYQITVPASFIKTEENRYE

Nucleotide

• Length: 789 bp

>AT101028 NZ_CP028355:3211693-3212481 [Shewanella baltica]
ATGTCATCAAAAATAAACTGGCTTATTAATCATACGAGTCCTGGTGCGGTAGTGCTTCAGTCGTGGTTGACACAAAATGA
GATCAGCTCATCTTTGGTGAGAAAATATGTGCAGAGTGGTTGGTTGTACAAGATAAGTGCGGGGGTTTACGTTCGTCCTG
AGTCAACAGGCAAGTTACAGCCTCATTGGGTTGAAGCGCTCAAGGCTGTGAATGAGCAGCTAAAGCTTCCTGTTCACCTT
GCGGGAGTTAGTAGCCTAACGTATCAAGGGCTTAGTCATTATCTTCAACTAAGCAGTGAGCAAGTTTGGGTTGGCTGTCA
AAGTAAGCAGGCGTTGCCAAAGTGGTTCCGTGAATTGGAGGCGCAAAACTGGCTTTTCTATACCAGTAGCAAGCTGACCC
AAACGTTGGAAAAAGACTTTATAACTATAGGGGTGAACAATAGGGAAGTTAAGGCAAGTTGTGCGGAGCTTGCCGCCTAT
GAGGTCGTCAATGCCATTGGCAAACATATCAGTTTTGAGCATGCCGCGGAGCTGTTTCAAGGGTTAGTGAATCTCAGCCC
ACGTAAAATCCAGTCAATACTGAATCGAAGTGAAGCCGTACAAGCTAATCGCGTATTTCTCTTTTTAGGTCACTACTATC
AACACCAGTGGAGCAAAAGGCTAGATGAGCAGCAAATCACGCTTGGTGCGGGAAAGCGTCAGGTGGTGGCTCATGGCCGT
TACGATGGACGCTATCAAATAACAGTGCCAGCATCGTTTATTAAGACAGAAGAAAATCGATATGAATAA