Detailed information of TA system TA101027

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 452862..453531
• Replicon: chromosome
• Accession: NZ_CP028355
• Organism: Shewanella baltica strain CW2

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: C8I07_RS01975
• Protein ID: WP_107402367.1
• Coordinates: 452862..453302 (-)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: C8I07_RS01980
• Protein ID: WP_107402368.1
• Coordinates: 453283..453531 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C8I07_RS01950	448339..448812	-	474	WP_107402366.1	SoxR reducing system RseC family protein	-
C8I07_RS01955	448823..449755	-	933	WP_006080775.1	MucB/RseB C-terminal domain-containing protein	-
C8I07_RS01960	449768..450394	-	627	WP_006080774.1	anti-sigma factor	-
C8I07_RS01965	450436..451014	-	579	WP_006080773.1	RNA polymerase sigma factor RpoE	-
C8I07_RS01970	451204..452817	+	1614	WP_006080772.1	L-aspartate oxidase	-
C8I07_RS01975	452862..453302	-	441	WP_107402367.1	hypothetical protein	Toxin
C8I07_RS01980	453283..453531	-	249	WP_107402368.1	succinate dehydrogenase assembly factor 2	Antitoxin
C8I07_RS01985	453617..454525	-	909	WP_063884532.1	transcriptional activator NhaR	-
C8I07_RS01990	454598..454984	-	387	WP_006080768.1	hypothetical protein	-
C8I07_RS01995	454987..456156	-	1170	WP_006080767.1	Na+/H+ antiporter NhaA	-
C8I07_RS02000	456274..457068	-	795	WP_006080766.1	thymidylate synthase	-
C8I07_RS02005	457065..457874	-	810	WP_107402369.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (6-135)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17316.39 Da
• Isoelectric Point: 7.7165

>T101027 WP_107402367.1 NZ_CP028355:c453302-452862 [Shewanella baltica]
VEDRHHSFSVKASFDQRLSLVVFICVCSSSFLLWPQSDNLALSLLKYLFILLVCVFLLSQMWRLQHWRLDFVLSDKGEGR
LSTGEHFQVLKRTWVTPFVCLMYIEVDTQLRLLMVWADMLEDTDYRHLCRLLLRAKIQQTKPHTEI

Nucleotide

• Length: 441 bp

>T101027 NZ_CP028355:c453302-452862 [Shewanella baltica]
GTGGAAGACCGGCACCATAGTTTCAGTGTAAAAGCCTCCTTCGACCAACGACTCTCGTTGGTCGTTTTTATTTGTGTCTG
TTCTAGCTCATTTTTGCTCTGGCCTCAAAGCGACAATCTCGCCTTATCCCTGCTTAAATATCTGTTTATCCTGCTAGTTT
GTGTTTTCTTGCTATCACAGATGTGGCGACTGCAGCATTGGCGTTTAGATTTTGTGCTTAGTGATAAAGGCGAGGGACGT
TTGTCAACGGGTGAGCACTTTCAGGTATTAAAGCGAACTTGGGTGACACCCTTTGTTTGCTTGATGTATATCGAAGTGGA
TACTCAGTTGCGGCTCTTGATGGTTTGGGCGGATATGCTAGAGGATACTGACTATCGGCATTTATGTCGGCTGTTGCTGC
GGGCTAAAATACAACAGACTAAACCTCATACTGAGATTTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9746.39 Da
• Isoelectric Point: 4.6510

>AT101027 WP_107402368.1 NZ_CP028355:c453531-453283 [Shewanella baltica]
MELMNIARVRWACRRGMLELDVLFQPFVEHFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDAELARMVVKVRGRP
AP

Nucleotide

• Length: 249 bp

>AT101027 NZ_CP028355:c453531-453283 [Shewanella baltica]
TTGGAATTAATGAACATCGCAAGGGTTCGCTGGGCATGTCGCCGCGGGATGCTGGAATTAGACGTTTTGTTTCAACCTTT
TGTTGAACATTTCTATCAAGAAATGTCCGATGAAGATAAAACCGTGTTTATCCGTTTGTTGGAATGTGAAGATCCCGAAT
TGTTTGCATGGTTTATGGGCCATGAAGTGTGCCCTGATGCTGAGCTTGCGCGCATGGTAGTGAAAGTCCGTGGAAGACCG
GCACCATAG