Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1160611..1161176 Replicon chromosome
Accession NZ_CP028341
Organism Bifidobacterium adolescentis strain 1-11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C8077_RS05175 Protein ID WP_107646255.1
Coordinates 1160611..1160901 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C8077_RS05180 Protein ID WP_107646256.1
Coordinates 1160898..1161176 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C8077_RS05165 1157601..1158524 - 924 WP_107646253.1 class C sortase -
C8077_RS05170 1158536..1159990 - 1455 WP_159042393.1 isopeptide-forming domain-containing fimbrial protein -
C8077_RS05175 1160611..1160901 - 291 WP_107646255.1 type II toxin-antitoxin system YafQ family toxin Toxin
C8077_RS05180 1160898..1161176 - 279 WP_107646256.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C8077_RS05185 1161697..1162329 - 633 WP_107646257.1 hypothetical protein -
C8077_RS05190 1162400..1162876 - 477 WP_107646258.1 hypothetical protein -
C8077_RS05195 1163008..1163874 + 867 WP_107646259.1 hypothetical protein -
C8077_RS05200 1163871..1164173 - 303 WP_107646260.1 hypothetical protein -
C8077_RS05205 1164170..1164598 - 429 WP_107646261.1 hypothetical protein -
C8077_RS05215 1164839..1165132 - 294 WP_107646263.1 hypothetical protein -
C8077_RS05220 1165268..1165495 - 228 WP_107646617.1 hypothetical protein -
C8077_RS05225 1165546..1165746 - 201 WP_107646264.1 hypothetical protein -
C8077_RS05230 1165759..1166070 - 312 WP_107646265.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10829.71 Da        Isoelectric Point: 9.8911

>T101006 WP_107646255.1 NZ_CP028341:c1160901-1160611 [Bifidobacterium adolescentis]
MRETKYAVKTTTKFKKDLRLAKRRGLDVSLLKEAISILATGGALPERYRDHALTGNLSGFRECHILPDLLLVYLMEEDVL
VLTLVRTGTHSDLFGK

Download         Length: 291 bp

>T101006 NZ_CP028341:c1160901-1160611 [Bifidobacterium adolescentis]
ATGAGAGAGACGAAATACGCGGTCAAAACAACCACGAAATTCAAAAAGGATCTCAGACTCGCGAAACGACGAGGCCTGGA
CGTCAGCCTGCTCAAAGAGGCGATTTCCATTCTGGCGACCGGCGGCGCACTCCCCGAGCGCTACCGTGACCATGCCCTCA
CCGGCAATCTGAGCGGATTCCGCGAATGCCACATCCTGCCGGACCTGCTGCTGGTCTATCTCATGGAAGAGGACGTATTG
GTGCTTACCCTGGTCCGCACAGGCACCCACAGCGATCTGTTCGGAAAATAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10277.64 Da        Isoelectric Point: 4.5994

>AT101006 WP_107646256.1 NZ_CP028341:c1161176-1160898 [Bifidobacterium adolescentis]
MAGTTTNINIRMDSELKKQAEALFGELGMNLTTAFNIFVRQSLRQGGIPFNVSLDRPNKETLTAMLEAERIAKDENTKGY
HDLDSLFGDLEI

Download         Length: 279 bp

>AT101006 NZ_CP028341:c1161176-1160898 [Bifidobacterium adolescentis]
ATGGCAGGAACAACCACGAACATCAATATCCGCATGGATTCCGAACTGAAGAAACAAGCCGAAGCGCTATTCGGCGAACT
GGGAATGAACCTGACGACCGCATTCAACATCTTCGTCCGCCAATCCCTCCGCCAGGGAGGAATCCCTTTCAACGTGTCGC
TCGACAGGCCCAACAAGGAAACCCTGACCGCCATGCTGGAGGCGGAACGGATAGCGAAAGACGAGAATACGAAGGGATAC
CACGATTTGGATAGCCTGTTCGGGGACCTGGAAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References