Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 1102609..1103124 Replicon chromosome
Accession NZ_CP028341
Organism Bifidobacterium adolescentis strain 1-11

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C8077_RS04955 Protein ID WP_107646213.1
Coordinates 1102873..1103124 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag C8077_RS04950 Protein ID WP_107646212.1
Coordinates 1102609..1102869 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C8077_RS04925 1098121..1098357 + 237 WP_107646207.1 hypothetical protein -
C8077_RS09335 1098354..1098539 + 186 WP_159042386.1 hypothetical protein -
C8077_RS04930 1098647..1099921 + 1275 WP_107646208.1 ArsR family transcriptional regulator -
C8077_RS04935 1099950..1100330 + 381 WP_107646209.1 hypothetical protein -
C8077_RS04940 1100586..1101548 + 963 WP_107646210.1 restriction endonuclease -
C8077_RS04945 1101781..1102392 + 612 WP_107646211.1 hypothetical protein -
C8077_RS04950 1102609..1102869 + 261 WP_107646212.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C8077_RS04955 1102873..1103124 + 252 WP_107646213.1 Txe/YoeB family addiction module toxin Toxin
C8077_RS04960 1103356..1105578 + 2223 WP_107646214.1 type IA DNA topoisomerase -
C8077_RS04965 1105639..1106220 - 582 WP_107646215.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-75)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9860.24 Da        Isoelectric Point: 7.9920

>T101005 WP_107646213.1 NZ_CP028341:1102873-1103124 [Bifidobacterium adolescentis]
MLRWSDDAWNDYLYWQGQDKKTLKRVNALIRDAMRSPFTGLGKPEPLKWELQGAWSRRIDSANRLVYMVEDGDLCILSVR
DHY

Download         Length: 252 bp

>T101005 NZ_CP028341:1102873-1103124 [Bifidobacterium adolescentis]
ATGCTGCGTTGGTCTGATGATGCGTGGAACGATTACTTGTATTGGCAGGGCCAGGATAAGAAGACCCTCAAAAGGGTCAA
CGCGTTGATACGTGACGCGATGCGTTCCCCGTTCACAGGCCTCGGCAAGCCCGAACCTCTCAAATGGGAATTGCAGGGCG
CGTGGAGTCGGCGCATAGACTCCGCGAACCGGCTGGTATACATGGTGGAAGACGGCGACCTGTGCATTCTGTCCGTCCGT
GATCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9757.98 Da        Isoelectric Point: 4.7393

>AT101005 WP_107646212.1 NZ_CP028341:1102609-1102869 [Bifidobacterium adolescentis]
MVTAVAYTNFRKDLKSYLRRVNDDADMLLVTNKDPQDNVVVMSADDYDSLMETLRVYQNPGLFDKVRRGMSQVRSGSAAA
HDLVEE

Download         Length: 261 bp

>AT101005 NZ_CP028341:1102609-1102869 [Bifidobacterium adolescentis]
ATGGTTACGGCGGTTGCATACACGAATTTTCGCAAGGATCTGAAATCGTATCTGCGTCGCGTGAACGACGATGCGGACAT
GCTCCTGGTCACCAACAAGGACCCGCAGGACAACGTGGTGGTGATGAGCGCCGACGATTACGACTCGCTCATGGAGACTC
TGCGCGTCTACCAGAACCCCGGATTGTTCGACAAGGTCCGTCGCGGGATGTCGCAGGTGCGGTCGGGTTCCGCTGCCGCG
CATGATCTGGTCGAGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References