Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3052652..3053205 Replicon chromosome
Accession NZ_CP028339
Organism Thauera aromatica K172

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Tharo_RS14450 Protein ID WP_107221798.1
Coordinates 3052912..3053205 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag Tharo_RS14445 Protein ID WP_107221797.1
Coordinates 3052652..3052924 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Tharo_RS17605 3049174..3049497 + 324 WP_159051711.1 DUF3325 family protein -
Tharo_RS14435 3049587..3050015 + 429 WP_107221796.1 heavy-metal-associated domain-containing protein -
Tharo_RS14440 3050100..3052214 - 2115 WP_211309621.1 TonB-dependent siderophore receptor -
Tharo_RS14445 3052652..3052924 + 273 WP_107221797.1 CopG family ribbon-helix-helix protein Antitoxin
Tharo_RS14450 3052912..3053205 + 294 WP_107221798.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Tharo_RS14455 3053304..3055448 - 2145 WP_107221799.1 heavy metal translocating P-type ATPase -
Tharo_RS14460 3055445..3055786 - 342 WP_107221800.1 hypothetical protein -
Tharo_RS14465 3055779..3056078 - 300 WP_107222449.1 hypothetical protein -
Tharo_RS14470 3056108..3056446 - 339 WP_107221801.1 hypothetical protein -
Tharo_RS14475 3056592..3056933 - 342 WP_107222450.1 heavy-metal-associated domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10750.30 Da        Isoelectric Point: 5.8498

>T101001 WP_107221798.1 NZ_CP028339:3052912-3053205 [Thauera aromatica K172]
VPQVIVTEGAAESLERCRRLLAAKAPEAARRAGQAIERQFLLLQTAPDIGRPFPEMPGLRELVIAFGDSGYVALYRYEAT
DDAVYVLAFRHQKEAGY

Download         Length: 294 bp

>T101001 NZ_CP028339:3052912-3053205 [Thauera aromatica K172]
GTGCCACAAGTAATCGTCACTGAAGGCGCAGCGGAAAGCTTGGAACGATGCCGGCGGCTCCTTGCCGCCAAGGCCCCGGA
AGCCGCCAGGCGGGCCGGCCAGGCCATTGAGCGGCAATTCCTGCTGCTGCAAACGGCTCCCGACATTGGCCGGCCGTTCC
CTGAAATGCCCGGGCTGCGTGAGCTGGTGATTGCCTTCGGGGACTCCGGCTATGTAGCCCTGTACCGCTACGAGGCGACC
GACGATGCGGTGTATGTTCTGGCCTTCCGACACCAGAAAGAGGCGGGCTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10575.83 Da        Isoelectric Point: 8.0869

>AT101001 WP_107221797.1 NZ_CP028339:3052652-3052924 [Thauera aromatica K172]
MATSLKIDDKLKSRVQHLASQRRRSPHRIMLEAIQQYVEREEARESFKQEALASWAAYQETGRHLSGQEVRTWLNTWGTD
DERPAPECHK

Download         Length: 273 bp

>AT101001 NZ_CP028339:3052652-3052924 [Thauera aromatica K172]
ATGGCAACGTCCCTCAAGATCGACGACAAGCTGAAAAGCCGCGTCCAGCACCTCGCCAGCCAGCGTCGCCGCTCGCCCCA
CAGGATCATGCTCGAAGCCATCCAGCAGTACGTCGAGCGCGAGGAAGCCCGCGAGAGCTTCAAGCAGGAAGCTTTGGCAT
CCTGGGCGGCCTATCAGGAAACCGGCCGGCACCTGAGCGGACAGGAAGTGCGCACTTGGTTGAACACCTGGGGCACCGAT
GACGAAAGGCCGGCGCCCGAGTGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References