Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 2073340..2073974 | Replicon | chromosome |
Accession | NZ_CP028339 | ||
Organism | Thauera aromatica K172 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | Tharo_RS09815 | Protein ID | WP_107221022.1 |
Coordinates | 2073340..2073741 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | Tharo_RS09820 | Protein ID | WP_107221023.1 |
Coordinates | 2073741..2073974 (-) | Length | 78 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
Tharo_RS09785 | 2069668..2071050 | - | 1383 | WP_107221018.1 | membrane-bound lytic murein transglycosylase MltF | - |
Tharo_RS09790 | 2071117..2071575 | - | 459 | WP_211309683.1 | cupin domain-containing protein | - |
Tharo_RS09795 | 2071759..2072046 | + | 288 | WP_107221019.1 | DUF1778 domain-containing protein | - |
Tharo_RS09800 | 2072031..2072537 | + | 507 | WP_211309589.1 | GNAT family N-acetyltransferase | - |
Tharo_RS17735 | 2072558..2072722 | - | 165 | WP_211309590.1 | WecB/TagA/CpsF family glycosyltransferase | - |
Tharo_RS09810 | 2072686..2073009 | - | 324 | WP_107221021.1 | DUF86 domain-containing protein | - |
Tharo_RS09815 | 2073340..2073741 | - | 402 | WP_107221022.1 | PIN domain-containing protein | Toxin |
Tharo_RS09820 | 2073741..2073974 | - | 234 | WP_107221023.1 | antitoxin | Antitoxin |
Tharo_RS17740 | 2074204..2074470 | + | 267 | WP_211309591.1 | hypothetical protein | - |
Tharo_RS09830 | 2074694..2075659 | - | 966 | WP_107221024.1 | magnesium/cobalt transporter CorA | - |
Tharo_RS09835 | 2075686..2077455 | - | 1770 | WP_107221025.1 | GGDEF domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 14478.68 Da Isoelectric Point: 6.9577
>T100999 WP_107221022.1 NZ_CP028339:c2073741-2073340 [Thauera aromatica K172]
MLRYLLDTNIVICVIKRRPLSALALFNENAGHLAISSITLAELMHGAEKSNAPARSLAAVEDFCCRLEVLPYGPKAAMHY
GNIRAQLESRGQTIGVNDLHIAAHARSEGLTLVSNNLGEFERVEALQLANWAA
MLRYLLDTNIVICVIKRRPLSALALFNENAGHLAISSITLAELMHGAEKSNAPARSLAAVEDFCCRLEVLPYGPKAAMHY
GNIRAQLESRGQTIGVNDLHIAAHARSEGLTLVSNNLGEFERVEALQLANWAA
Download Length: 402 bp
>T100999 NZ_CP028339:c2073741-2073340 [Thauera aromatica K172]
ATGCTGCGCTACCTGCTCGACACGAACATCGTAATCTGCGTGATCAAGCGCCGGCCGCTGTCGGCACTTGCGCTGTTCAA
CGAGAACGCCGGGCATCTGGCGATCTCGTCGATTACCCTCGCGGAGCTGATGCACGGCGCCGAGAAAAGCAACGCGCCAG
CGCGTTCGCTTGCCGCTGTCGAGGACTTCTGCTGTCGCCTCGAGGTGCTGCCCTACGGCCCGAAAGCAGCAATGCACTAT
GGCAACATCCGCGCCCAACTGGAATCTCGCGGGCAGACAATCGGCGTCAATGATCTGCACATTGCAGCACACGCACGTAG
CGAGGGTCTGACGCTCGTTTCGAACAACTTGGGCGAGTTCGAGCGAGTGGAAGCATTACAGTTGGCTAACTGGGCAGCCT
GA
ATGCTGCGCTACCTGCTCGACACGAACATCGTAATCTGCGTGATCAAGCGCCGGCCGCTGTCGGCACTTGCGCTGTTCAA
CGAGAACGCCGGGCATCTGGCGATCTCGTCGATTACCCTCGCGGAGCTGATGCACGGCGCCGAGAAAAGCAACGCGCCAG
CGCGTTCGCTTGCCGCTGTCGAGGACTTCTGCTGTCGCCTCGAGGTGCTGCCCTACGGCCCGAAAGCAGCAATGCACTAT
GGCAACATCCGCGCCCAACTGGAATCTCGCGGGCAGACAATCGGCGTCAATGATCTGCACATTGCAGCACACGCACGTAG
CGAGGGTCTGACGCTCGTTTCGAACAACTTGGGCGAGTTCGAGCGAGTGGAAGCATTACAGTTGGCTAACTGGGCAGCCT
GA
Antitoxin
Download Length: 78 a.a. Molecular weight: 8744.84 Da Isoelectric Point: 7.0120
>AT100999 WP_107221023.1 NZ_CP028339:c2073974-2073741 [Thauera aromatica K172]
MTTSTVFTNNRSQAVRLPADMRLPANVKRVDVRARGLERIIAPVGHTWDSFFINGPQVADDFMETRASQEQQEREAL
MTTSTVFTNNRSQAVRLPADMRLPANVKRVDVRARGLERIIAPVGHTWDSFFINGPQVADDFMETRASQEQQEREAL
Download Length: 234 bp
>AT100999 NZ_CP028339:c2073974-2073741 [Thauera aromatica K172]
ATGACTACAAGTACCGTCTTCACGAACAATCGCAGCCAGGCCGTGCGACTGCCGGCAGACATGCGCTTGCCCGCGAACGT
CAAGCGCGTGGACGTCCGGGCCCGCGGGTTGGAGCGGATCATCGCGCCGGTAGGCCACACGTGGGATTCGTTCTTCATCA
ACGGGCCGCAGGTTGCCGACGATTTCATGGAAACCCGCGCCAGCCAGGAACAGCAGGAACGCGAGGCGCTCTGA
ATGACTACAAGTACCGTCTTCACGAACAATCGCAGCCAGGCCGTGCGACTGCCGGCAGACATGCGCTTGCCCGCGAACGT
CAAGCGCGTGGACGTCCGGGCCCGCGGGTTGGAGCGGATCATCGCGCCGGTAGGCCACACGTGGGATTCGTTCTTCATCA
ACGGGCCGCAGGTTGCCGACGATTTCATGGAAACCCGCGCCAGCCAGGAACAGCAGGAACGCGAGGCGCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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