Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2906636..2906904 Replicon chromosome
Accession NZ_CP028320
Organism Escherichia coli O18:H1 strain CFSAN067215

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2906674..2906776 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2906636..2906904 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7X15_RS14570 2903793..2905232 + 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C7X15_RS14575 2905350..2905586 + 237 WP_001295499.1 DUF1480 family protein -
C7X15_RS14580 2905691..2905882 + 192 WP_001317886.1 YebW family protein -
C7X15_RS14585 2905883..2906539 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 2906636..2906904 + 269 - - Antitoxin
- 2906674..2906776 - 103 - - Toxin
C7X15_RS14590 2906934..2907275 - 342 WP_000984819.1 YebY family protein -
C7X15_RS14595 2907288..2908160 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
C7X15_RS14600 2908164..2908538 - 375 WP_000168747.1 CopC domain-containing protein YobA -
C7X15_RS14605 2908677..2908907 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C7X15_RS14610 2909010..2909666 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
C7X15_RS14615 2909690..2910352 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T100967 NZ_CP028320:c2906776-2906674 [Escherichia coli O18:H1]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT100967 NZ_CP028320:2906636-2906904 [Escherichia coli O18:H1]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References