Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2658691..2658962 | Replicon | chromosome |
| Accession | NZ_CP028192 | ||
| Organism | Escherichia coli strain CFSAN018748 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2658821..2658924 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2658691..2658962 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C7A99_RS13760 | 2654536..2655198 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| C7A99_RS13765 | 2655222..2655878 | - | 657 | WP_000011651.1 | carbon-nitrogen hydrolase family protein | - |
| C7A99_RS13770 | 2655979..2656209 | - | 231 | WP_107235878.1 | DNA polymerase III subunit theta | - |
| C7A99_RS13775 | 2656348..2656722 | + | 375 | WP_001578488.1 | CopC domain-containing protein YobA | - |
| C7A99_RS13780 | 2656726..2657598 | + | 873 | WP_107235879.1 | copper homeostasis membrane protein CopD | - |
| C7A99_RS13785 | 2657611..2657952 | + | 342 | WP_000976481.1 | YebY family protein | - |
| C7A99_RS13790 | 2658088..2658546 | - | 459 | WP_159042828.1 | IS200/IS605 family transposase | - |
| - | 2658691..2658962 | - | 272 | - | - | Antitoxin |
| - | 2658821..2658924 | + | 104 | - | - | Toxin |
| C7A99_RS13800 | 2659059..2659715 | + | 657 | WP_000812713.1 | protein-serine/threonine phosphatase | - |
| C7A99_RS13805 | 2659716..2659907 | - | 192 | WP_001296140.1 | YebW family protein | - |
| C7A99_RS13810 | 2660012..2660248 | - | 237 | WP_105273509.1 | DUF1480 family protein | - |
| C7A99_RS13815 | 2660366..2661805 | - | 1440 | WP_107236327.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2636138..2675513 | 39375 | |
| - | flank | IS/Tn | - | - | 2658088..2658546 | 458 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T100821 NZ_CP028192:2658821-2658924 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT100821 NZ_CP028192:c2658962-2658691 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
