Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 5413236..5413807 Replicon chromosome
Accession NZ_CP028159
Organism Plantactinospora sp. BB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6W10_RS23555 Protein ID WP_199853516.1
Coordinates 5413547..5413807 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6W10_RS23550 Protein ID WP_107260578.1
Coordinates 5413236..5413520 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6W10_RS23525 5408699..5410099 - 1401 WP_107260569.1 amidase -
C6W10_RS23530 5410147..5411289 - 1143 WP_107260571.1 cystathionine gamma-synthase -
C6W10_RS23535 5411313..5411726 + 414 WP_107260572.1 HIT family protein -
C6W10_RS23540 5411716..5412288 - 573 WP_107260574.1 hypothetical protein -
C6W10_RS23545 5412481..5413140 + 660 WP_107260576.1 peptide-methionine (S)-S-oxide reductase MsrA -
C6W10_RS23550 5413236..5413520 + 285 WP_107260578.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C6W10_RS23555 5413547..5413807 + 261 WP_199853516.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6W10_RS23560 5413840..5413926 + 87 Protein_4684 peptide-methionine (S)-S-oxide reductase -
C6W10_RS23565 5414297..5415280 + 984 WP_107260582.1 ribonuclease Z -
C6W10_RS23570 5415240..5415578 - 339 WP_199853734.1 MmcQ/YjbR family DNA-binding protein -
C6W10_RS23575 5415596..5416123 + 528 WP_107260586.1 GNAT family N-acetyltransferase -
C6W10_RS23580 5416231..5417187 + 957 WP_107260588.1 trypsin-like peptidase domain-containing protein -
C6W10_RS23585 5417225..5418601 - 1377 WP_107260590.1 cystathionine beta-synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(24-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9650.05 Da        Isoelectric Point: 9.9738

>T100690 WP_199853516.1 NZ_CP028159:5413547-5413807 [Plantactinospora sp. BB1]
MQVAGPAARALAGRLPEKIAAAVYEFITTALLDNPHRVGKRLLLPPFQGTWSARRGTYRVLYEIDEDDRVVTVTAIEHRA
DAYRSR

Download         Length: 261 bp

>T100690 NZ_CP028159:5413547-5413807 [Plantactinospora sp. BB1]
CTGCAGGTCGCCGGCCCGGCCGCACGCGCCTTGGCCGGGCGGCTGCCAGAGAAGATCGCCGCAGCCGTCTACGAGTTCAT
CACCACCGCCCTCCTCGACAACCCGCATCGCGTCGGCAAACGACTGCTTCTGCCACCGTTCCAGGGAACCTGGTCGGCCA
GACGGGGCACGTATCGAGTCCTCTACGAGATCGACGAGGACGACCGCGTCGTGACCGTGACGGCCATAGAACATCGCGCC
GACGCCTACCGGTCGCGTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10114.41 Da        Isoelectric Point: 4.4537

>AT100690 WP_107260578.1 NZ_CP028159:5413236-5413520 [Plantactinospora sp. BB1]
MTVVPFTDARNRLSELIDEVTSTHERIEITKHGHAAAVLISADDLAALEETLEVLSSAEAMRQLAESKAAVEAGDVLDAD
ELAALMAKRSKQAR

Download         Length: 285 bp

>AT100690 NZ_CP028159:5413236-5413520 [Plantactinospora sp. BB1]
ATGACTGTCGTGCCGTTCACCGACGCTCGCAACCGCCTCTCAGAACTCATCGACGAGGTGACCTCGACCCATGAGCGGAT
AGAGATCACCAAACACGGCCACGCCGCCGCGGTGCTCATCTCCGCCGACGATCTCGCGGCTTTGGAAGAGACGCTGGAGG
TCCTGTCCAGCGCTGAAGCCATGCGGCAACTTGCCGAATCCAAGGCAGCCGTCGAAGCCGGTGACGTTCTCGACGCCGAC
GAACTCGCGGCGTTGATGGCGAAGCGGTCGAAGCAGGCACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References