Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 4615348..4615919 Replicon chromosome
Accession NZ_CP028158
Organism Plantactinospora sp. BC1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C6361_RS20225 Protein ID WP_199853516.1
Coordinates 4615348..4615608 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C6361_RS20230 Protein ID WP_107268659.1
Coordinates 4615635..4615919 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6361_RS20195 4610553..4611929 + 1377 WP_107260590.1 cystathionine beta-synthase -
C6361_RS20200 4611967..4612923 - 957 WP_107268657.1 trypsin-like peptidase domain-containing protein -
C6361_RS20205 4613030..4613557 - 528 WP_107268658.1 GNAT family N-acetyltransferase -
C6361_RS20210 4613614..4613913 + 300 WP_199853027.1 MmcQ/YjbR family DNA-binding protein -
C6361_RS20215 4613873..4614856 - 984 WP_107271056.1 ribonuclease Z -
C6361_RS20220 4615229..4615315 - 87 Protein_3999 peptide-methionine (S)-S-oxide reductase -
C6361_RS20225 4615348..4615608 - 261 WP_199853516.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6361_RS20230 4615635..4615919 - 285 WP_107268659.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C6361_RS20235 4616014..4616673 - 660 WP_107268660.1 peptide-methionine (S)-S-oxide reductase MsrA -
C6361_RS20240 4616871..4617437 + 567 WP_199853517.1 hypothetical protein -
C6361_RS20245 4617427..4617840 - 414 WP_107268662.1 HIT family protein -
C6361_RS20250 4617864..4619006 + 1143 WP_107268663.1 cystathionine gamma-synthase -
C6361_RS20255 4619054..4620454 + 1401 WP_107260569.1 amidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(24-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9650.05 Da        Isoelectric Point: 9.9738

>T100689 WP_199853516.1 NZ_CP028158:c4615608-4615348 [Plantactinospora sp. BC1]
MQVAGPAARALAGRLPEKIAAAVYEFITTALLDNPHRVGKRLLLPPFQGTWSARRGTYRVLYEIDEDDRVVTVTAIEHRA
DAYRSR

Download         Length: 261 bp

>T100689 NZ_CP028158:c4615608-4615348 [Plantactinospora sp. BC1]
CTGCAGGTCGCCGGGCCGGCCGCACGCGCCTTGGCCGGGCGGCTGCCAGAGAAGATCGCCGCAGCCGTCTACGAGTTCAT
CACCACCGCCCTCCTCGACAACCCGCATCGCGTCGGCAAACGACTGCTTCTGCCACCGTTCCAGGGAACCTGGTCGGCCA
GACGGGGCACGTATCGAGTCCTCTACGAGATCGACGAGGACGACCGCGTCGTGACCGTGACGGCCATAGAACATCGCGCC
GACGCCTACCGGTCGCGTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10144.43 Da        Isoelectric Point: 4.4537

>AT100689 WP_107268659.1 NZ_CP028158:c4615919-4615635 [Plantactinospora sp. BC1]
MTVVPFTDARNRLSELIDEVTSTHERIEITKHGHTAAVLISADDLAALEETLEVLSSAEAMRQLAESKAAVEAGDVLDAD
ELAALMAKRSKQAR

Download         Length: 285 bp

>AT100689 NZ_CP028158:c4615919-4615635 [Plantactinospora sp. BC1]
ATGACTGTCGTGCCCTTCACCGACGCTCGCAACCGCCTCTCAGAACTCATCGACGAGGTGACCTCGACCCATGAGCGGAT
AGAGATCACCAAACACGGCCACACCGCCGCGGTACTCATCTCCGCCGACGATCTCGCGGCTTTGGAAGAGACGCTGGAGG
TCCTGTCCAGCGCTGAAGCCATGCGGCAACTTGCCGAATCCAAGGCAGCCGTCGAAGCCGGTGACGTTCTCGACGCCGAC
GAACTCGCGGCGTTGATGGCGAAGCGGTCGAAGCAGGCACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References